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评估非肥胖、肥胖和重度肥胖慢性肌肉骨骼疾病患者的数字康复效果。

Evaluating Digital Rehabilitation Outcomes in Chronic Musculoskeletal Conditions Across Non-Obesity, Obesity, and Severe Obesity.

作者信息

Pereira Ana P, Janela Dora, Areias Anabela C, Molinos Maria, Tong Xin, Bento Virgílio, Yanamadala Vijay, Cohen Steven P, Correia Fernando Dias, Costa Fabíola

机构信息

Sword Health, Inc, Draper, Utah, USA.

Department of Psychology, University of Virginia, Charlottesville, VA, USA.

出版信息

J Pain Res. 2025 Jan 7;18:73-87. doi: 10.2147/JPR.S499846. eCollection 2025.

Abstract

BACKGROUND

Obesity is a known risk factor and aggravator of musculoskeletal (MSK) conditions. The rising prevalence of obesity calls for scalable solutions to address MSK conditions in this population, given their complex clinical profile and barriers to accessing care.

PURPOSE

To evaluate the engagement and clinical outcomes of a fully remote digital care program in patients with MSK conditions, focusing on those with and without comorbid obesity.

PATIENTS AND METHODS

A post-hoc analysis of a prospective, longitudinal, single-arm observational home-based study conducted between August, 2023, and August, 2024. Adults suffering from chronic MSK pain were categorized according to their body mass index (BMI) into non-obesity, obesity and severe obesity. Outcomes included completion rates, engagement, satisfaction, pain (minimal clinically important change: 30%), impairment in daily activities, and patient global impression of change (PGIC). Depending on the clinical outcomes, latent basis growth analysis and logistic regression were used.

RESULTS

Completion rates were high across all groups (77.5-85.6%), although slightly lower in the obesity groups. Fairly similar engagement was observed with both exercise sessions and the educational content (1.9-2.2 exercise sessions per week; 8.10-9.31 educational content videos watched). Obesity groups interacted more with the physical therapists than the non-obesity group (severe obesity: 24.6 (SD 10.1); obesity: 23.2 (SD 10.46) vs non-obesity: 22.4 (SD 9.8), P < 0.001). Despite higher baseline risk and clinical impairment in the obesity groups, all groups showed significant pain reductions, with pain responder rates ranging from 56.6 to 63.6%, slightly lower in the severe obesity group. Improvements in daily activities were significant across groups, alongside a positive PGIC (50.4-53.6%). Satisfaction was very high (>9/10) in all BMI groups.

CONCLUSION

Despite worse baseline clinical presentations, obesity groups achieved high completion rates, engagement, and significant clinical improvements comparable to the non-obesity group, highlighting the potential of a digital program for this population.

摘要

背景

肥胖是已知的肌肉骨骼(MSK)疾病的风险因素和加重因素。鉴于肥胖人群复杂的临床特征和获得护理的障碍,肥胖患病率的上升需要可扩展的解决方案来解决该人群的MSK疾病。

目的

评估一项完全远程数字护理计划在MSK疾病患者中的参与度和临床结果,重点关注有无合并肥胖的患者。

患者与方法

对2023年8月至2024年8月进行的一项前瞻性、纵向、单臂观察性家庭研究进行事后分析。患有慢性MSK疼痛的成年人根据其体重指数(BMI)分为非肥胖、肥胖和重度肥胖。结果包括完成率、参与度、满意度、疼痛(最小临床重要变化:30%)、日常活动受损情况以及患者整体变化印象(PGIC)。根据临床结果,使用潜在基础增长分析和逻辑回归。

结果

所有组的完成率都很高(77.5 - 85.6%),尽管肥胖组略低。在锻炼课程和教育内容方面观察到的参与度相当相似(每周1.9 - 2.2次锻炼课程;观看8.10 - 9.31个教育内容视频)。肥胖组与物理治疗师的互动比非肥胖组更多(重度肥胖:24.6(标准差10.1);肥胖:23.2(标准差10.46) vs 非肥胖:22.4(标准差9.8),P < 0.001)。尽管肥胖组的基线风险和临床损伤较高,但所有组的疼痛均显著减轻,疼痛缓解率在56.6%至63.6%之间,重度肥胖组略低。各组日常活动均有显著改善,同时PGIC呈阳性(50.4 - 53.6%)。所有BMI组的满意度都非常高(>9/10)。

结论

尽管基线临床表现较差,但肥胖组的完成率、参与度较高,且临床改善程度与非肥胖组相当,凸显了数字计划对该人群的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/700d/11724668/4d54da6ab4cf/JPR-18-73-g0001.jpg

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