Kim Sunghye, Brooks Amber K, Groban Leanne
Department of Hospital Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Clin Interv Aging. 2014 Dec 16;10:13-27. doi: 10.2147/CIA.S75285. eCollection 2015.
Nearly 50% of Americans will have an operation after the age of 65 years. Traditional preoperative anesthesia consultations capture only some of the information needed to identify older patients (defined as ≥65 years of age) undergoing elective surgery who are at increased risk for postoperative complications, prolonged hospital stays, and delayed or hampered functional recovery. As a catalyst to this review, we compared traditional risk scores (eg, cardiac-focused) to geriatric-specific risk measures from two older female patients seen in our preoperative clinic who were scheduled for elective, robotic-assisted hysterectomies. Despite having a lower cardiac risk index and Charlson comorbidity score, the younger of the two patients presented with more subtle negative geriatric-specific risk predictors - including intermediate or pre-frail status, borderline malnutrition, and reduced functional/mobility - which may have contributed to her 1-day-longer length of stay and need for readmission. Adequate screening of physiologic and cognitive reserves in older patients scheduled for surgery could identify at-risk, vulnerable elders and enable proactive perioperative management strategies (eg, strength, balance, and mobility prehabilitation) to reduce adverse postoperative outcomes and readmissions. Here, we describe our initial two cases and review the stress response to surgery and the impact of advanced age on this response as well as preoperative geriatric assessments, including frailty, nutrition, physical function, cognition, and mood state tests that may better predict postoperative outcomes in older adults. A brief overview of the literature on anesthetic techniques that may influence geriatric-related syndromes is also presented.
近50%的美国人在65岁之后会接受手术。传统的术前麻醉会诊只能获取部分识别接受择期手术的老年患者(定义为年龄≥65岁)所需的信息,这些患者术后并发症风险增加、住院时间延长、功能恢复延迟或受阻。作为此次综述的一个契机,我们将传统风险评分(如针对心脏的评分)与我们术前门诊见到的两位计划接受择期机器人辅助子宫切除术的老年女性患者的老年特异性风险指标进行了比较。尽管其中较年轻的患者心脏风险指数和查尔森合并症评分较低,但她存在一些更细微的老年特异性负面风险预测因素,包括中度或虚弱前期状态、边缘性营养不良以及功能/活动能力下降,这些因素可能导致她住院时间延长1天并需要再次入院。对计划手术的老年患者进行充分的生理和认知储备筛查,可以识别出有风险的脆弱老年人,并制定积极的围手术期管理策略(如力量、平衡和活动能力预康复),以减少术后不良后果和再次入院情况。在此,我们描述我们最初的两个病例,并回顾手术应激反应以及高龄对该反应的影响,以及术前老年评估,包括可能更好地预测老年人术后结局的衰弱、营养、身体功能、认知和情绪状态测试。还简要概述了可能影响老年相关综合征的麻醉技术文献。