Li Jie, Yang Wenjie, Wang Zhe
Institute for Prevention and Control of STD and AIDS, Henan Provincial Center for Diseases Control and Prevention, Zhengzhou 450016, China.
Institute for Prevention and Control of STD and AIDS, Henan Provincial Center for Diseases Control and Prevention, Zhengzhou 450016, China. Email:
Zhonghua Liu Xing Bing Xue Za Zhi. 2014 Oct;35(10):1119-22.
To describe the epidemiological characteristics and changing trend of HCV-related children in Henan province.
Data was analyzed based on the case-reporting records on hepatitis C from 2008 to 2013.
The number of reported cases and incidence of HCV-related children had increased annually from 2008 to 2012. The reported incidence on HCV-related children increased from 2.37 per 100 000 in 2008, to 3.23 per 100 000 in 2012, but it decreased to 1.77 per 100 000 in 2013. Reported cases on females increased annually. The 0-1 age group had the largest proportion but it decreased annually. Large cities as Zhengzhou, had high incidence, and the mobile population within the province also showed an annual increase, from 49.02% in 2008, to 59.77% in 2013. Time between onset and diagnosis(days) of the disease increased and the M and IQR from 2008 to 2013 appeared as 0(0-2), 0(0-2), 1(0-2), 1(0-3), 1(0-5) and 1(0-3).
The incidence of HCV-related children in Henan province showed an annual increase, along with the increasing trend of mobile population in the province as well as the longer time span between onset and diagnosis of the disease. It is suggested that strengthening the program on monitor, as well as on effective prevention and control measures be in place accordingly. Targets should also be focused on pregnant women, migrants, other key groups, so as to better perform on early detection and treatment.
描述河南省丙型肝炎病毒（HCV）相关儿童的流行病学特征及变化趋势。
基于2008年至2013年丙型肝炎病例报告记录进行数据分析。
2008年至2012年，HCV相关儿童报告病例数和发病率逐年上升。HCV相关儿童报告发病率从2008年的每10万2.37例增至2012年的每10万3.23例，但2013年降至每10万1.77例。女性报告病例数逐年增加。0 - 1岁年龄组占比最大，但逐年下降。像郑州这样的大城市发病率较高，省内流动人口也呈逐年上升趋势，从2008年的49.02%升至2013年的59.77%。发病至诊断的时间（天）增加，2008年至2013年的中位数及四分位数间距分别为0(0 - 2)、0(0 - 2)、1(0 - 2)、1(0 - 3)、1(0 - 5)和1(0 - 3)。
河南省HCV相关儿童发病率呈逐年上升趋势，同时省内流动人口呈上升趋势且发病至诊断时间延长。建议加强监测工作及相应有效的预防控制措施。还应关注孕妇、流动人口等重点人群，以便更好地进行早期检测和治疗。
