Fu Weijie, Hu Maohong, Liu Xiaoqing, Xie Yun, Xiong Ying, Pan Huanhong
Jiangxi Provincial Center for Disease Control and Prevention, Nanchang 330029, China.
Nanchang Municipal Center for Disease Control and Prevention.
Zhonghua Liu Xing Bing Xue Za Zhi. 2014 Oct;35(10):1131-4.
To analyze and discuss the source and epidemic disposition of human infection with avian influenza A (H10N8) virus.
Epidemiological surveys were used to collect related data and RT-PCR was applied to detect the specimens collected from cases, close contacts related exposure to live poultry markets. Data were analyzed descriptively.
Three cases were discovered by surveillance on patients with severe pneumonia, two of the three died, but one in the hospital with the course over 6 months. All the three cases had histories of exposure to live poultry or related markets. Lower respiratory tract gargle aspirate samples of 3 patients were detected by Nanchang Municipal Center for Disease Control and Prevention (CDC) and Jiangxi Provincial CDC, and the results showed the influenza 2009pdmH1, H3, H5, H7, H9 subtypes negative. Specimen of patient 1 and 2 was positive for influenza A universal primers. Specimen of patient 3 was positive for H10N8 detected by Chinese National Influenza Center. All 33 close contacts of the patients were negative for H10N8 virus. Positive rate of the total poultry environmental specimens collected from the cases exposure markets was 5.19%. No new cases were found, after the prevention and control messages were implemented.
Three cases of H10N8 avian influenza virus infection province might be associated with exposure to live poultry market in Jiangxi.
分析和探讨人感染甲型H10N8禽流感病毒的来源及流行特征。
采用流行病学调查收集相关数据，应用逆转录-聚合酶链反应（RT-PCR）检测病例、密切接触者及相关活禽市场采集的标本。对数据进行描述性分析。
通过对重症肺炎患者监测发现3例病例，其中2例死亡，1例住院病程超过6个月。3例病例均有活禽或相关市场暴露史。南昌市疾病预防控制中心（CDC）和江西省CDC对3例患者的下呼吸道漱口液标本进行检测，结果显示2009年甲型H1、H3、H5、H7、H9亚型流感病毒均为阴性。患者1和2的标本甲型流感通用引物检测为阳性。患者3的标本经中国国家流感中心检测H10N8为阳性。33例患者密切接触者H10N8病毒检测均为阴性。病例暴露市场采集的禽类环境标本总阳性率为5.19%。防控措施落实后未发现新发病例。
江西省3例H10N8禽流感病毒感染病例可能与接触江西活禽市场有关。
