Al-Ghorabie Fayez H H
Department of Physics, Faculty of Science, Umm Al-Qura University, Makkah, Saudi Arabia. Tel.: +966 12 5270000; Fax: +966 12 5564560; E-mail:
J Xray Sci Technol. 2015;23(1):57-64. doi: 10.3233/XST-140470.
An EGSnrc user code is developed to simulate a backscattered geometry in vivo x-ray fluorescence system for the measurement of platinum concentration in head and neck tumours. The user code is fundamentally based on a previous study which used the EGS4 Monte Carlo code. The new user code, which we have developed in this study, has new improvements which made it able to simulate the process of photon transportation through the different components of the modelled x-ray fluorescence system. The simulation process included modelling of the photon source, collimators, phantoms and detector. Simulation results were compared and evaluated against x-ray fluorescence data obtained experimentally from an existing system developed by the Swansea In vivo Analysis and Cancer Research Group. In addition, simulation results of this study were also compared with our previous study in which the EGS4 user code was used. Comparison between results has shown that the new EGSnrc user code was able to reproduce the spectral shape obtained using the experimental x-ray fluorescence system. The area under the Compton peak differs by 2.5% between the experimental measurement and the EGSnrc simulation. Similarly, the area under the two Pt Kα peaks differs by 2.3% and 2.2%.
开发了一个EGSnrc用户代码，用于模拟体内X射线荧光系统中的反向散射几何结构，以测量头颈肿瘤中的铂浓度。该用户代码基本上基于之前一项使用EGS4蒙特卡罗代码的研究。我们在本研究中开发的新用户代码有新的改进，使其能够模拟光子通过建模的X射线荧光系统不同组件的传输过程。模拟过程包括对光子源、准直器、体模和探测器进行建模。将模拟结果与从斯旺西体内分析与癌症研究小组开发的现有系统实验获得的X射线荧光数据进行比较和评估。此外，本研究的模拟结果还与我们之前使用EGS4用户代码的研究进行了比较。结果比较表明，新的EGSnrc用户代码能够重现使用实验性X射线荧光系统获得的光谱形状。康普顿峰下的面积在实验测量和EGSnrc模拟之间相差2.5%。同样，两个铂Kα峰下的面积相差2.3%和2.2%。
