Marazzi Chiara, Scoditti Umberto, Ticinesi Andrea, Nouvenne Antonio, Pigna Federica, Guida Loredana, Morelli Ilaria, Borghi Loris, Meschi Tiziana
Post-Graduate School of Emergency-Urgency Medicine, University of Parma, Parma, Italy.
Acta Biomed. 2014 Dec 17;85(3):229-35.
Transient Global Amnesia (TGA) is a clinical syndrome characterized by temporary inability to form new memories described as anterograde amnesia. It is associated with retrograde amnesia and repetitive questioning. During the attack patients remain conscious and communicative and personal identity is preserved. Focal neurological symptoms and epileptic features are absent and general conditions appear intact. The ability to store new memories gradually recovers and subjects return to normal conditions except for a substantial amnestic gap for the duration of the attack. TGA has an incidence of 3-8 per 100 000 people per year. It usually affects patients between the ages of 50 and 70 years, at an average age of 61 years; occurrence in patients younger than 40 years of age is rare. The rate of recurrence is between 6% and 10% per years. No gender prevalence has been recorded. The patients with definite TGA have a very good prognosis; their rate of subsequent major vascular events is less than 1% per year.
短暂性全面性遗忘症(TGA)是一种临床综合征,其特征为暂时无法形成新记忆,即顺行性遗忘。它与逆行性遗忘和反复提问有关。发作期间,患者保持清醒且能交流,个人身份得以保留。无局灶性神经症状和癫痫特征,一般状况似乎完好。存储新记忆的能力逐渐恢复,除了发作期间存在明显的遗忘间隙外,患者恢复到正常状态。TGA的发病率为每年每10万人中有3 - 8例。它通常影响50至70岁的患者,平均年龄为61岁;40岁以下患者发病罕见。每年的复发率在6%至10%之间。未记录到性别差异。确诊为TGA的患者预后非常好;其随后发生重大血管事件的比率每年低于1%。