Chen Yin-Yin, Li Anna Fen-Yau, Huang Kuo-Hung, Lan Yuan-Tzu, Chen Ming-Huang, Chao Yee, Lo Su-Shun, Wu Chew-Wun, Shyr Yi-Ming, Fang Wen-Liang
Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Rd., Beitou District, Taipei, 11217, Taiwan.
Pathol Oncol Res. 2015 Jul;21(3):547-51. doi: 10.1007/s12253-014-9890-7. Epub 2015 Jan 8.
Adenosquamous carcinoma of the stomach is a very rare disease, consisting of less than 0.4 % of all stomach cancer. From 1991 to 2013, a total of 2800 patients received gastrectomy for gastric cancer at Taipei Veterans General hospital. Among them, seven patients (0.25 %) diagnosed as adenosquamous carcinoma were enrolled. The clinicopathologic characteristics and prognosis were analyzed. The mean age of the seven patients was 62.3 years-old. There were 5 males and 2 females. Six patients were stage III disease and one patient was stage IV disease. Four patients finally died of gastric cancer. Only one patient had no recurrence until death. Among the seven patients, adenocarcinoma component comprises the majority of the metastatic lymph node in 6 patients (85.7 %). The only one patient with major squamous cell carcinoma component in metastatic lymph node had no tumor recurrence till death. Adenosquamous carcinoma of stomach is a rare disease and is associated with a poor prognosis. The component of adenocarcinoma and squamous cell carcinoma in the metastatic lymph node may influence the prognosis.
胃腺鳞癌是一种非常罕见的疾病，占所有胃癌的比例不到0.4%。1991年至2013年，台北荣民总医院共有2800例患者因胃癌接受了胃切除术。其中，7例（0.25%）被诊断为胃腺鳞癌并被纳入研究。对其临床病理特征和预后进行了分析。这7例患者的平均年龄为62.3岁。男性5例，女性2例。6例患者为III期疾病，1例患者为IV期疾病。4例患者最终死于胃癌。只有1例患者直至死亡都未复发。在这7例患者中，6例（85.7%）的转移淋巴结中腺癌成分占多数。转移淋巴结中主要为鳞状细胞癌成分的唯一1例患者直至死亡都没有肿瘤复发。胃腺鳞癌是一种罕见疾病，预后较差。转移淋巴结中腺癌和鳞状细胞癌的成分可能会影响预后。
