Siebachmeyer M, Boddu K, Bilal A, Hester T W, Hardwick T, Fox T P, Edmonds M, Kavarthapu V
King's College Hospital NHS Foundation Trust, London SE5 9RT, UK.
Bone Joint J. 2015 Jan;97-B(1):76-82. doi: 10.1302/0301-620X.97B1.34542.
We report the outcomes of 20 patients (12 men, 8 women, 21 feet) with Charcot neuro-arthropathy who underwent correction of deformities of the ankle and hindfoot using retrograde intramedullary nail arthrodesis. The mean age of the patients was 62.6 years (46 to 83); their mean BMI was 32.7 (15 to 47) and their median American Society of Anaesthetists score was 3 (2 to 4). All presented with severe deformities and 15 had chronic ulceration. All were treated with reconstructive surgery and seven underwent simultaneous midfoot fusion using a bolt, locking plate or a combination of both. At a mean follow-up of 26 months (8 to 54), limb salvage was achieved in all patients and 12 patients (80%) with ulceration achieved healing and all but one patient regained independent mobilisation. There was failure of fixation with a broken nail requiring revision surgery in one patient. Migration of distal locking screws occurred only when standard screws had been used but not with hydroxyapatite-coated screws. The mean American Academy of Orthopaedic Surgeons Foot and Ankle (AAOS-FAO) score improved from 50.7 (17 to 88) to 65.2 (22 to 88), (p = 0.015). The mean Short Form (SF)-36 Health Survey Physical Component Score improved from 25.2 (16.4 to 42.8) to 29.8 (17.7 to 44.2), (p = 0.003) and the mean Euroqol EQ‑5D‑5L score improved from 0.63 (0.51 to 0.78) to 0.67 (0.57 to 0.84), (p = 0.012). Single-stage correction of deformity using an intramedullary hindfoot arthrodesis nail is a good form of treatment for patients with severe Charcot hindfoot deformity, ulceration and instability provided a multidisciplinary care plan is delivered.
我们报告了20例患有夏科特神经关节病的患者(12名男性,8名女性,21只脚)的治疗结果,这些患者采用逆行髓内钉关节融合术对踝关节和后足畸形进行了矫正。患者的平均年龄为62.6岁(46至83岁);平均体重指数为32.7(15至47),美国麻醉医师协会评分中位数为3(2至4)。所有患者均表现为严重畸形,15例有慢性溃疡。所有患者均接受了重建手术,7例同时使用螺栓、锁定钢板或两者结合进行了中足融合。平均随访26个月(8至54个月)时,所有患者均实现了保肢,12例(80%)溃疡患者实现了愈合,除1例患者外,所有患者均恢复了独立活动能力。1例患者出现髓内钉断裂需要翻修手术的内固定失败情况。仅在使用标准螺钉时发生远端锁定螺钉移位,而使用羟基磷灰石涂层螺钉时未发生。美国矫形外科医师学会足踝(AAOS-FAO)平均评分从50.7(17至88)提高到65.2(22至88),(p = 0.015)。简明健康调查(SF)-36身体成分平均评分从25.2(16.4至42.8)提高到29.8(17.7至44.2),(p = 0.003),欧洲五维度健康量表(Euroqol)EQ-5D-5L平均评分从0.63(0.51至0.78)提高到0.67(0.57至0.84),(p = 0.012)。对于患有严重夏科特后足畸形、溃疡和不稳定的患者,采用髓内后足关节融合钉进行一期畸形矫正,是一种很好的治疗方式,前提是实施多学科护理计划。