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局部获取的自体骨移植物对于治疗足部和踝关节夏科氏神经关节病的融合是有效的:来自北非足部和踝关节外科专业单位的短期至中期结果。

Locally obtained autologous bone grafts are effective for achieving arthrodesis while managing foot and ankle charcot's neuroarthropathy: short to mid-term results from a specialized north African foot and ankle surgery unit.

机构信息

Orthopaedic Department, Assiut University Hospital, Assiut, Egypt.

Orthopaedic Department, Qena faculty of medicine and University Hospital, South Valley University, Qena, Egypt.

出版信息

J Orthop Surg Res. 2024 Sep 16;19(1):570. doi: 10.1186/s13018-024-05036-9.

Abstract

PURPOSE

We aimed to report the union rate after only utilizing a locally obtained autologous bone graft while correcting the deformity and performing joint arthrodesis in patients with foot and ankle Charcot neuropathy (CN) and to report on the radiographic, functional, complications incidence outcomes at a minimum of two years of follow up.

METHODS

We included 24 patients having a mean age of 55.4 ± 10.1 years diagnosed with CN of the foot, ankle, or both. Seven (29.2%) cases were classified as Brodsky type 1, 11 (45.8%) as type 3 A, and six (25%) were type 4. Hindfoot and Midfoot bi-columnar arthrodesis was performed in 70.8% and 29.2% of the patients, respectively. Eight (33.3%) cases had preoperative ulcers. Functional outcomes were evaluated using a modified AOFAS score. Arthrodesis site union was assessed clinically and radiographically. All patients were available for a mean follow up of 35.7 ± 9.5 (24-54) months.

RESULTS

Arthrodesis site union was achieved in 23 (95.8%) cases after a mean of 4 ± 1.7 (2-7.5) months. The mean modified AOFAS score was 72.4 ± 10.41 (46-83) points; 79.2% achieved excellent and good scores. Ulcers healed in 87.5% of the patients. Twenty-two (91.7%) patients were satisfied with their functional results. Infection incidence was 12.5%, and no patients required revision or amputation.

CONCLUSION

Foot and ankle Charcot neuroarthropathy deformity correction by arthrodesis of the affected joint as a salvage management option resulted in acceptable clinical and radiological outcomes. To enhance the local environment for arthrodesis consolidation, locally obtained autografts led to higher union rates and avoided the drawbacks of using other graft types.

摘要

目的

本研究旨在报告仅利用局部获取的自体骨移植物治疗足部和踝关节夏科氏神经病(CN)患者的畸形和关节融合,以及在至少 2 年的随访后评估其影像学、功能和并发症发生率结果。

方法

我们纳入了 24 名平均年龄为 55.4±10.1 岁的 CN 患者,这些患者足部、踝关节或两者均有病变。7 例(29.2%)患者为 Brodsky 1 型,11 例(45.8%)为 3A 型,6 例(25%)为 4 型。70.8%的患者行全距下和中跗骨双柱融合术,29.2%的患者行单柱融合术。8 例(33.3%)患者术前有溃疡。采用改良 AOFAS 评分评估功能结果。通过临床和影像学评估融合部位愈合情况。所有患者平均随访 35.7±9.5(24-54)个月。

结果

23 例(95.8%)患者在平均 4±1.7(2-7.5)个月后达到融合部位愈合。平均改良 AOFAS 评分为 72.4±10.41(46-83)分;79.2%的患者获得优秀和良好评分。87.5%的患者溃疡愈合。22 例(91.7%)患者对其功能结果满意。感染发生率为 12.5%,无患者需要翻修或截肢。

结论

作为挽救性治疗选择,通过受累关节融合矫正足部和踝关节夏科氏神经病畸形可获得可接受的临床和影像学结果。为了增强融合固定的局部环境,使用局部获取的自体移植物可提高融合率,并避免使用其他移植物类型的缺点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b835/11406869/cad492e7b4db/13018_2024_5036_Fig1_HTML.jpg

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