• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

多发性结肠息肉病

Multiple colon polyposis.

作者信息

Buturovic Sead

机构信息

General hospital Konjic, Konjic, Bosnia and Herzegovina.

出版信息

Med Arch. 2014 Jun;68(3):221-2. doi: 10.5455/medarh.2014.68.221-222. Epub 2014 May 31.

DOI:10.5455/medarh.2014.68.221-222
PMID:25568540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4240332/
Abstract

INTRODUCTION

Familial adenomatous polyposis (FAP) is a rare autosomal, dominant hereditary disease, which affects both sexes equally (1-10). FAP accounts for less than 1% of all colon cancers and is estimated to occur in one of 8,300 live births. It is characterized by numerous adenomas scattered throughout mucosa of the colon and rectum.

CASE REPORT

The patient is a 62 years old man, admitted at the Surgical Department of the General Hospital in Konjic on May 18 2010 with gastrointestinal problems including: hard stool, often splattered with fresh blood, irregular and that causes the patient a lot of problems. The final diagnosis was median laparatomy supra et infraumibilicalis. Exploratio cavi abdominalis. Colectomy totalis et ileo-recto anastomosis TT cum staypler (33Ch). Loop ileostomy. Drainage cavi abdominalis N I (uno). Early postoperative course was generally regular. Control laboratory findings show the reference value. After ten days of hospitalization, the patient was discharged on the home recovery, with practically given instructions for care and use of stoma bags. For the secondary surgery was planned ileostomy closure, and regular post-operative endoscopic control.

CONCLUSION

Most of the listed surgical intervention in case of FAP treatment localized in the colon can be performed by open (classic), or laparoscopic methods. Duration of postoperative stay in the hospital depends on the patient's general condition and the type of performed surgery. It is usually about 7 days. After hospital treatment, recovery at home is from 4-6 weeks. Patients can usually return to work or school 6-8 weeks after surgery. After surgery, patients lives will be completely normal. Sexual and social activities remain the same, while either procedure does not affect the ability of a man or woman to have offspring.

摘要

引言

家族性腺瘤性息肉病(FAP)是一种罕见的常染色体显性遗传性疾病,男女发病率相同(1 - 10)。FAP在所有结肠癌中占比不到1%,据估计每8300例活产中会有1例发病。其特征是结肠和直肠黏膜上散在着大量腺瘤。

病例报告

患者为一名62岁男性,于2010年5月18日因胃肠道问题入住科尼茨综合医院外科,这些问题包括:大便干结,常带有鲜血,排便不规律,给患者带来诸多困扰。最终诊断为经脐上下正中剖腹术。腹腔探查。全结肠切除术及回肠 - 直肠端端吻合术(33Ch),使用吻合器。回肠袢式造口术。腹腔引流(1根)。术后早期病程总体正常。实验室检查结果显示在参考值范围内。住院十天后,患者出院回家康复,并得到了关于造口袋护理和使用的实际指导。计划进行二次手术关闭回肠造口,并进行定期的术后内镜检查。

结论

FAP治疗中多数涉及结肠的手术干预可通过开放(经典)或腹腔镜方法进行。术后住院时间取决于患者的一般状况和所施行手术的类型。通常约为7天。出院后在家恢复需要4 - 6周。患者通常在术后6 - 8周可返回工作或学校。手术后,患者的生活将完全正常。性活动和社交活动保持不变,且两种手术方式均不影响男性或女性的生育能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf2a/4240332/71c3bda4ab51/MA-68-221-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf2a/4240332/3cced150873f/MA-68-221-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf2a/4240332/71c3bda4ab51/MA-68-221-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf2a/4240332/3cced150873f/MA-68-221-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf2a/4240332/71c3bda4ab51/MA-68-221-g002.jpg

相似文献

1
Multiple colon polyposis.多发性结肠息肉病
Med Arch. 2014 Jun;68(3):221-2. doi: 10.5455/medarh.2014.68.221-222. Epub 2014 May 31.
2
Multiple colon polyposis.多发性结肠息肉病。
Med Arh. 2014;68(3):221-2.
3
[Laparoscopic total colectomy (TPC) for familial adenomatous polyposis - a case report].[腹腔镜全结肠切除术治疗家族性腺瘤性息肉病——病例报告]
Gan To Kagaku Ryoho. 2014 Nov;41(12):1634-6.
4
Laparoscopic total colectomy and ileorectal anastomosis (IRA), supported by an enhanced recovery programme in cases of familial adenomatous polyposis.腹腔镜全结肠切除和回直肠吻合术(IRA),在家族性腺瘤性息肉病的情况下,通过强化康复方案支持。
Colorectal Dis. 2012 Apr;14(4):458-62. doi: 10.1111/j.1463-1318.2011.02683.x.
5
Colonic Surgery in Patients With Familial Adenomatous Polyposis.家族性腺瘤性息肉病患者的结肠手术。
Dis Colon Rectum. 2019 Jul;62(7):781-785. doi: 10.1097/DCR.0000000000001408.
6
Successful local excision of ileostomy adenocarcinoma after colectomy for familial adenomatous polyposis: report of a case.家族性腺瘤性息肉病行结肠切除术后回肠造口腺癌的成功局部切除:病例报告
Surg Today. 2002;32(7):638-41. doi: 10.1007/s005950200116.
7
[Familial adenomatous polyposis with extracolonic manifestations--case report].[家族性腺瘤性息肉病伴结肠外表现——病例报告]
Acta Med Croatica. 2004;58(5):411-5.
8
Segmental resection with primary anastomosis is not always safe in splenic flexure perforation.对于脾曲穿孔,一期吻合的节段性切除并不总是安全的。
BMC Res Notes. 2016 Jan 16;9:27. doi: 10.1186/s13104-016-1841-9.
9
The ileo neo-rectal anastomosis in patients with familial adenomatous polyposis: a prospective case series with long-term follow up.家族性腺瘤性息肉病患者的回肠新直肠吻合术:一项具有长期随访的前瞻性病例系列研究。
Colorectal Dis. 2012 Jul;14(7):861-5. doi: 10.1111/j.1463-1318.2011.02806.x.
10
Familial adenomatous polyposis.家族性腺瘤性息肉病
J Coll Physicians Surg Pak. 2011 Jan;21(1):46-8.

引用本文的文献

1
Current status of familial gastrointestinal polyposis syndromes.家族性胃肠息肉综合征的现状
World J Gastrointest Oncol. 2015 Nov 15;7(11):347-55. doi: 10.4251/wjgo.v7.i11.347.

本文引用的文献

1
Different phenotype manifestation of familial adenomatous polyposis in families with APC mutation at codon 1309.密码子1309处APC基因突变家族中家族性腺瘤性息肉病的不同表型表现。
Neoplasma. 2009;56(6):486-9. doi: 10.4149/neo_2009_06_486.
2
Adrenal incidentaloma in familial adenomatous polyposis: a long-term follow-up study and schema for management.家族性腺瘤性息肉病中的肾上腺偶发瘤:一项长期随访研究及管理方案
Dis Colon Rectum. 2009 Sep;52(9):1637-44. doi: 10.1007/DCR.0b013e3181a876d6.
3
High resolution endoscopy and the additional value of chromoendoscopy in the evaluation of duodenal adenomatosis in patients with familial adenomatous polyposis.
高分辨率内镜检查及色素内镜检查在家族性腺瘤性息肉病患者十二指肠腺瘤病评估中的附加价值。
Endoscopy. 2009 Aug;41(8):666-9. doi: 10.1055/s-0029-1214980. Epub 2009 Aug 10.
4
Desmoid tumors in a dutch cohort of patients with familial adenomatous polyposis.荷兰家族性腺瘤性息肉病患者队列中的硬纤维瘤
Clin Gastroenterol Hepatol. 2008 Feb;6(2):215-9. doi: 10.1016/j.cgh.2007.11.011.
5
Fundic gland polyp dysplasia is common in familial adenomatous polyposis.胃底腺息肉发育异常在家族性腺瘤性息肉病中很常见。
Clin Gastroenterol Hepatol. 2008 Feb;6(2):180-5. doi: 10.1016/j.cgh.2007.11.018.
6
Capsule endoscopy is useful and safe for small-bowel surveillance in familial adenomatous polyposis.胶囊内镜检查对于家族性腺瘤性息肉病的小肠监测是有用且安全的。
Gastrointest Endosc. 2008 Jan;67(1):61-7. doi: 10.1016/j.gie.2007.07.048.
7
BubR1 and APC/EB1 cooperate to maintain metaphase chromosome alignment.BubR1和APC/EB1共同协作以维持中期染色体排列。
J Cell Biol. 2007 Aug 27;178(5):773-84. doi: 10.1083/jcb.200702138. Epub 2007 Aug 20.
8
Increased epithelial cell proliferation in the ileal pouch mucosa of patients with familial adenomatous polyposis.家族性腺瘤性息肉病患者回肠储袋黏膜上皮细胞增殖增加。
Virchows Arch. 2007 Sep;451(3):659-67. doi: 10.1007/s00428-007-0451-2. Epub 2007 Jul 5.
9
Hereditary colorectal cancer: risk assessment and management.遗传性结直肠癌:风险评估与管理
Clin Genet. 2000 Aug;58(2):89-97. doi: 10.1034/j.1399-0004.2000.580201.x.
10
Familial adenomatous polyposis.家族性腺瘤性息肉病
Semin Surg Oncol. 2000 Jun;18(4):314-23. doi: 10.1002/(sici)1098-2388(200006)18:4<314::aid-ssu6>3.0.co;2-9.