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精子计数对被诊断为男性因素不育的夫妇宫内人工授精成功率的影响。

Effect of sperm count on success of intrauterine insemination in couples diagnosed with male factor infertility.

作者信息

Zhang Erhong, Tao Xin, Xing Weijie, Cai Liuhong, Zhang Bin

机构信息

Department of Infertility and Sexual Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

出版信息

Mater Sociomed. 2014 Oct;26(5):321-3. doi: 10.5455/msm.2014.26.321-323. Epub 2014 Oct 29.

Abstract

OBJECTIVE

To exam semen parameters in predicting intrauterine insemination (IUI) outcomes in couples with male factor.

STUDY DESIGN

This retrospective study was performed at department of infertility and sexual medicine from September 2007 to February 2014. 307 couples with male factor infertility were included and 672 IUI cycles were analyzed.

RESULTS

From 672 inseminations performed on 307 couples, there are 27.36% couples get pregnancy (84 out of 307) and the overall pregnancy rate was 12.95% (87 out of 672) of IUI. With the increase of post total progressive sperm count, the clinical pregnancy rate increased. When the initial progressive sperm count was lower than 5*10(6), there was no pregnant in the IUI cycle. At the end of the third cycle, 85 clinical pregnancies had been achieved (97.70%).

CONCLUSIONS

The initial total progressive sperm count lower than 5*10(6) means the poor outcome of IUI in the infertile couples with male factor. If the infertile couples with male factor don't get pregnancy after three IUI cycles, the couples should receive re-assessment or other artificial reproductive technology.

摘要

目的

研究精液参数对男性因素不孕夫妇宫内人工授精(IUI)结局的预测价值。

研究设计

本回顾性研究于2007年9月至2014年2月在不孕与性医学科进行。纳入307对男性因素不孕夫妇,分析672个IUI周期。

结果

对307对夫妇进行的672次授精中,27.36%的夫妇妊娠(307对中的84对),IUI的总体妊娠率为12.95%(672次中的87次)。随着射精后总活动精子数增加,临床妊娠率升高。当初始活动精子数低于5×10⁶时,IUI周期无妊娠发生。在第三个周期结束时,共获得85例临床妊娠(97.70%)。

结论

初始总活动精子数低于5×10⁶意味着男性因素不孕夫妇IUI结局不佳。若男性因素不孕夫妇经三个IUI周期仍未妊娠,应重新评估或接受其他辅助生殖技术。

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