a Department of Medicine , Division of Gastroenterology, University of British Columbia , Vancouver , British Columbia , Canada.
b Division of Gastroenterology, Department of Medicine, St. Paul's Hospital , University of British Columbia , Vancouver , Canada.
Crit Rev Food Sci Nutr. 2016 Jun 10;56(8):1370-8. doi: 10.1080/10408398.2012.760515.
Diet may be a successful part of the treatment plan for improving outcome in patients with inflammatory bowel disease (IBD). This study aimed to systematically review all published clinical trials evaluating the effects of a regular diet on symptoms of IBD. Three medical databases were searched for clinical trials evaluating an intervention that involved dietary manipulation using a regular diet on adults with IBD whose symptoms were objectively measured before and after the intervention. The most common types of regular diet interventions that we observed in the literature fell into the following three categories: low residue/low fiber diets, exclusion diets, or other specific diets. Of all included studies, the few that were of higher quality and that observed a statistically significant improvement in symptoms in the diet group compared to the control group fell under the exclusion diet group or the other specific diet group. We were able to identify several high quality clinical trials evaluating dietary manipulations on symptoms of IBD. Exclusion diets and the low FODMAP diet are two areas identified in this review that show promise for having therapeutic benefits for patients with IBD.
饮食可能是改善炎症性肠病(IBD)患者治疗效果的成功部分。本研究旨在系统地回顾所有已发表的临床试验,评估常规饮食对 IBD 症状的影响。我们检索了三个医学数据库,以寻找评估干预措施的临床试验,这些干预措施涉及使用常规饮食对 IBD 成人进行饮食干预,这些患者的症状在干预前后均经过客观测量。我们在文献中观察到的最常见的常规饮食干预类型分为以下三类:低残渣/低纤维饮食、排除饮食或其他特定饮食。在所有纳入的研究中,少数高质量的研究观察到饮食组与对照组相比症状有统计学意义的改善,这些研究属于排除饮食组或其他特定饮食组。我们能够确定几项评估饮食对 IBD 症状影响的高质量临床试验。本综述确定了排除饮食和低 FODMAP 饮食两个有治疗潜力的领域,对 IBD 患者可能具有治疗益处。