Tripathy Nirmalya, Ahmad Rafiq, Ko Hyun Ah, Khang Gilson, Hahn Yoon-Bong
Department of BIN Fusion Technology and Polymer BIN Research Center, Chonbuk National University, 567 Baekje-daero, Deokjin-gu, Jeonju 561-756, Republic of Korea.
Chem Commun (Camb). 2015 Feb 14;51(13):2585-8. doi: 10.1039/c4cc10037a.
ZnO platforms were evaluated for designing a high-performance anticancer drug (daunorubicin) carrier. Hollow structured ZnO, compared with nanorods, acts as a multi-purpose entity by serving as smart carriers and exhibiting synergetic photodynamic cytotoxic effects, which are ascribed to their high-specific surface area, hollow interior, pH-responsiveness and inherent photodynamism.
对氧化锌平台进行了评估,以设计一种高性能的抗癌药物(柔红霉素)载体。与纳米棒相比,中空结构的氧化锌作为一种多功能实体,可作为智能载体,并表现出协同光动力细胞毒性作用,这归因于其高比表面积、中空内部、pH响应性和固有的光动力特性。