Tripathy Nirmalya, Kim Deok-Ho
Department of Bioengineering, University of Washington, Seattle, WA, 98109, USA.
Center for Cardiovascular Biology, University of Washington, Seattle, WA, 98109, USA.
Nano Converg. 2018 Oct 3;5(1):27. doi: 10.1186/s40580-018-0159-9.
Advancing as a biosensing nanotechnology, nanohybrids present a new class of functional materials with high selectivity and sensitivity, enabling integration of nanoscale chemical/biological interactions with biomedical devices. The unique properties of ZnO combined with metal oxide nanostructures were recently demonstrated to be an efficient approach for sensor device fabrication with accurate, real-time and high-throughput biosensing, creating new avenues for diagnosis, disease management and therapeutics. This review article collates recent advances in the modified ZnO nanostructured metal oxide nanohybrids for efficient enzymatic and non-enzymatic biosensor applications. Furthermore, we also discussed future prospects for nanohybrid materials to yield high-performance biosensor devices.
作为一种生物传感纳米技术，纳米杂化物呈现出一类具有高选择性和灵敏度的新型功能材料，能够将纳米级化学/生物相互作用与生物医学设备集成。最近证明，ZnO与金属氧化物纳米结构相结合的独特性能是制造具有准确、实时和高通量生物传感功能的传感器设备的有效方法，为诊断、疾病管理和治疗开辟了新途径。本文综述了用于高效酶促和非酶促生物传感器应用的改性ZnO纳米结构金属氧化物纳米杂化物的最新进展。此外，我们还讨论了纳米杂化材料产生高性能生物传感器设备的未来前景。
