O'Clock George D
Annu Int Conf IEEE Eng Med Biol Soc. 2014;2014:3021-5. doi: 10.1109/EMBC.2014.6944259.
Regulation, growth and healing in biological systems involve many interconnected and interdependent processes that include chemical and electrical mechanisms of action. Unfortunately, the significant contributions that electrical events provide are often overlooked; resulting in a poor transfer of knowledge from science, to engineering and finally to therapy. Wound site electrical processes can influence cell migration, fluid transport, cellular signaling events, gene expression, cell differentiation and cell proliferation; affecting both form and function at the cell, tissue and organ levels. Wound healing, and its interrelationships with transport, regeneration, and growth, cannot be understood or therapeutically assisted unless both chemical and electrical activities associated with the healing process are addressed.
生物系统中的调节、生长和愈合涉及许多相互关联和相互依存的过程，其中包括化学和电作用机制。不幸的是，电活动所起的重要作用常常被忽视；导致知识从科学到工程，最终到治疗的传递不佳。伤口部位的电过程会影响细胞迁移、液体运输、细胞信号传导事件、基因表达、细胞分化和细胞增殖；在细胞、组织和器官水平上影响形态和功能。除非解决与愈合过程相关的化学和电活动，否则无法理解伤口愈合及其与运输、再生和生长的相互关系，也无法提供治疗帮助。
