Wernick Naomi L B, Ndung'u Eric, Haughton Dominique, Ledley Fred D
Department of Natural and Applied Sciences, Bentley University, Waltham, MA 02452 ; Department of Biological Sciences, University of Massachusetts Lowell, MA 01854.
Department of Mathematical Sciences, Bentley University, Waltham, MA 02452.
J Microbiol Biol Educ. 2014 Dec 15;15(2):268-76. doi: 10.1128/jmbe.v15i2.724. eCollection 2014 Dec.
Biological thought increasingly recognizes the centrality of the genome in constituting and regulating processes ranging from cellular systems to ecology and evolution. In this paper, we ask whether genomics is similarly positioned as a core concept in the instructional sequence for undergraduate biology. Using quantitative methods, we analyzed the order in which core biological concepts were introduced in textbooks for first-year general and human biology. Statistical analysis was performed using self-organizing map algorithms and conventional methods to identify clusters of terms and their relative position in the books. General biology textbooks for both majors and nonmajors introduced genome-related content after text related to cell biology and biological chemistry, but before content describing higher-order biological processes. However, human biology textbooks most often introduced genomic content near the end of the books. These results suggest that genomics is not yet positioned as a core concept in commonly used textbooks for first-year biology and raises questions about whether such textbooks, or courses based on the outline of these textbooks, provide an appropriate foundation for understanding contemporary biological science.
生物学思想越来越认识到基因组在构成和调节从细胞系统到生态与进化等一系列过程中的核心地位。在本文中,我们探讨基因组学在本科生物学教学序列中是否同样处于核心概念的位置。我们运用定量方法,分析了一年级普通生物学和人体生物学教材中引入核心生物学概念的顺序。使用自组织映射算法和传统方法进行统计分析,以识别术语集群及其在教材中的相对位置。无论是面向专业学生还是非专业学生的普通生物学教材,都是在介绍与细胞生物学和生物化学相关的内容之后,才引入与基因组相关的内容,但在描述高阶生物学过程的内容之前。然而,人体生物学教材大多在书的结尾附近才引入基因组相关内容。这些结果表明,在常用的一年级生物学教材中,基因组学尚未被定位为核心概念,这也引发了关于此类教材或基于这些教材大纲的课程是否为理解当代生物科学提供了合适基础的问题。