探寻人类造血干细胞的特性。
In search of human hematopoietic stem cell identity.
机构信息
MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, Scotland, UK.
MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, Scotland, UK.
出版信息
Cell Stem Cell. 2015 Jan 8;16(1):5-6. doi: 10.1016/j.stem.2014.12.010.
Better insight into hematopoietic stem cell (HSC) development in the human embryo and fetus is crucial for translational research. In this issue of Cell Stem Cell, Prashad et al. (2014) describe a novel surface marker for human fetal liver HSCs, glycosylphosphatidylinositol-anchored protein GPI-80, that is functionally required for their self-renewal.
深入了解人类胚胎和胎儿造血干细胞（HSC）的发育对于转化研究至关重要。在本期《细胞-干细胞》杂志上，Prashad 等人（2014）描述了一种用于鉴定人类胎儿肝脏 HSC 的新型表面标志物——糖基磷脂酰肌醇锚定蛋白 GPI-80，它对于 HSC 的自我更新具有功能必需性。
Zotero 插件