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[病例报告——亚硝酸烷基酯(“Poppers”)摄入后的危险中毒]

[Case report - a dangerous intoxication after ingestion of alkyl nitrite ("poppers")].

作者信息

Bernasconi Barbara, Konrad Christoph, Fischer Simon

出版信息

Anasthesiol Intensivmed Notfallmed Schmerzther. 2014 Dec;49(11-12):654-8. doi: 10.1055/s-0040-100107. Epub 2015 Jan 9.

DOI:10.1055/s-0040-100107
PMID:25575230
Abstract

This case report describes the inadvertent poisoning of a young man with "poppers" after having ingested an unknown amout of the drug. "Poppers" (alkyl nitrite) were made famous in the 1960s as a party drug, and during certain sexual practices, and are still in use today. The drug's inhalation leads to a short-lived rush, vasodilation and relaxtion of smooth muscles. An accidental ingestion can lead to a significant build-up of methemoglobin with dire consequences. The therapy consists of the intravenous administration of methylene blue.

摘要

本病例报告描述了一名年轻男子在摄入未知量的“Poppers”后意外中毒的情况。“Poppers”(亚硝酸烷基酯)在20世纪60年代作为一种派对药物而声名远扬,在某些性行为中也有使用,至今仍在使用。吸入该药物会导致短暂的兴奋、血管舒张和平滑肌松弛。意外摄入可导致高铁血红蛋白大量积聚,后果严重。治疗方法包括静脉注射亚甲蓝。

相似文献

1
[Case report - a dangerous intoxication after ingestion of alkyl nitrite ("poppers")].[病例报告——亚硝酸烷基酯(“Poppers”)摄入后的危险中毒]
Anasthesiol Intensivmed Notfallmed Schmerzther. 2014 Dec;49(11-12):654-8. doi: 10.1055/s-0040-100107. Epub 2015 Jan 9.
2
Dangerous intoxication after oral ingestion of poppers (alkyl nitrites): Two case reports.口服Poppers(亚硝酸烷基酯)后的危险中毒:两例报告。
Therapie. 2017 Jun;72(3):397-399. doi: 10.1016/j.therap.2016.09.005. Epub 2016 Dec 2.
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Do not turn a blind eye to alkyl nitrite (poppers)!不要对亚硝酸烷基酯(Poppers)视而不见!
Acta Ophthalmol. 2016 Feb;94(1):e82-3. doi: 10.1111/aos.12753. Epub 2015 May 14.
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[Amyl nitrite: drugs and intoxicants].[亚硝酸异戊酯:药物与毒品]
Ugeskr Laeger. 1996 Sep 30;158(40):5645-6.
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The poppers-HIV connection.Poppers与艾滋病病毒的关联。
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Acute haemolytic anaemia after inhalation of amyl nitrite.吸入亚硝酸异戊酯后急性溶血性贫血
J R Soc Med. 2003 Dec;96(12):594-5. doi: 10.1177/014107680309601209.
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Oxidative haemolysis due to 'poppers'.因“Poppers”导致的氧化性溶血。
Br J Haematol. 2008 Jul;142(3):328. doi: 10.1111/j.1365-2141.2008.07150.x. Epub 2008 May 8.
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'Poppers' dermatitis.“Poppers”皮炎。
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[Methemoglobinemia due to ingestion of isobutyl nitrite ('poppers')].因摄入亚硝酸异丁酯(“Poppers”)导致的高铁血红蛋白血症
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"Poppers" or "snappers" dermatitis in homosexual men.男同性恋者中的“Poppers”或“snappers”皮炎
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引用本文的文献

1
An Update on Deaths in the United Kingdom from 'Poppers' (Alkyl Nitrites), with a Particular Focus on 'Swallowing' Fatalities.英国因“Poppers”(亚硝酸烷基酯)致死情况的最新报告,特别关注“吞咽”导致的死亡案例。
J Clin Med. 2025 Jan 10;14(2):427. doi: 10.3390/jcm14020427.
2
Nitrites: An Old Poison or a Current Hazard? Epidemiology of Intoxications Covering the Last 100 Years and Evaluation of Analytical Methods.亚硝酸盐:古老的毒药还是当前的危害?过去100年中毒情况的流行病学及分析方法评估
Toxics. 2023 Oct 1;11(10):832. doi: 10.3390/toxics11100832.
3
Lessons of the month 3: Intravenous poppers abuse: case report, management and possible complications.
本月经验教训3:静脉注射Poppers滥用:病例报告、管理及可能的并发症
Clin Med (Lond). 2020 Mar;20(2):221-223. doi: 10.7861/clinmed.2019-0469.
4
[Methemoglobinemia after inhalation of poppers].吸入Poppers后发生的高铁血红蛋白血症
Med Klin Intensivmed Notfmed. 2019 May;114(4):345-349. doi: 10.1007/s00063-018-0441-y. Epub 2018 Apr 17.