Reisinger Alexander, Vogt Susanne, Essl Anna, Rauch Ines, Bangerl Florian, Eller Philipp, Hackl Gerald
Medical University of Graz, Graz, Austria and Austrian Red Cross, Graz, Austria
University Medical Center, Freiburg, Germany.
Clin Med (Lond). 2020 Mar;20(2):221-223. doi: 10.7861/clinmed.2019-0469.
Poppers are nitrite-containing liquids, which are inhaled for their aphrodisiac and hallucinogenic effects. Despite some cases of severe poisonings, poppers are often perceived as harmless by consumers. Inhalation and ingestion of poppers are well known, but, according to our literature review, intravenous abuse has not been reported before.
A 34-year-old man injected poppers intravenously for recreational purposes. He then suffered from dyspnoea and general discomfort. Upon arrival of emergency medical services, the patient was dyspnoeic with blue-grey skin colour and oxygen saturation was 82% on ambient air. Non-invasive ventilation was necessary, and he was transferred to the intensive care unit. Toluidine blue was administered because of a methaemoglobinaemia of 40% and methaemoglobin levels dropped to 0.4%. He was discharged home after a 24-hour observation. We additionally analysed the contents of the poppers bottle: isopropyl nitrite, isopropanol and acetone were detected. Possible complications and the treatment regarding intravenous administration of poppers are discussed.
We present the first published case of intravenous poppers abuse. Our patient suffered from methaemoglobinaemia and was rapidly discharged after treatment with toluidine blue. No specific treatment regarding the contents of the poppers bottle, apart from isopropyl nitrite, was necessary.
Poppers是一种含亚硝酸盐的液体，因其催情和致幻作用而被吸入。尽管有一些严重中毒的案例，但消费者通常认为Poppers是无害的。吸入和摄入Poppers是众所周知的，但根据我们的文献综述，此前尚未有静脉滥用的报道。
一名34岁男子出于娱乐目的静脉注射Poppers。随后他出现呼吸困难和全身不适。紧急医疗服务人员到达时，患者呼吸困难，皮肤呈蓝灰色，在空气中的氧饱和度为82%。需要进行无创通气，并将他转入重症监护病房。由于高铁血红蛋白血症达40%，给予甲苯胺蓝治疗，高铁血红蛋白水平降至0.4%。经过24小时观察后，他出院回家。我们还分析了Poppers瓶中的成分：检测到亚硝酸异丙酯、异丙醇和丙酮。讨论了静脉注射Poppers可能出现的并发症及治疗方法。
我们报告了首例关于静脉滥用Poppers的病例。我们的患者患有高铁血红蛋白血症，经甲苯胺蓝治疗后迅速出院。除亚硝酸异丙酯外，对于Poppers瓶中的成分无需进行特殊治疗。
