抗苗勒管激素的测定：一种新型超灵敏免疫测定法的性能
Measurement of anti-Mullerian hormone: performances of a new ultrasensitive immunoassay.
作者信息
Gruson Damien, Homsak Evgenija
机构信息
Pôle de recherche en Endocrinologie, Diabète et Nutrition, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires St-Luc, Université Catholique de Louvain, Brussels, Belgium; Department of Laboratory Medicine, Cliniques Universitaires St-Luc, Université Catholique de Louvain, Brussels, Belgium.
Department of Laboratory Diagnosis, University Clinical Centre Maribor, Maribor, Slovenia.
出版信息
Clin Biochem. 2015 Apr;48(6):453-5. doi: 10.1016/j.clinbiochem.2014.12.023. Epub 2015 Jan 6.
The measurement of anti-Mullerian hormone (AMH) is relevant for the evaluation of primary ovarian insufficiency, success of assisted reproductive therapies, and also to support the diagnosis of polycystic ovary syndrome. Our study demonstrated excellent analytical performances for the Ansh Laboratories AMH immunoassay and an overall good agreement with the AMH Gen II assay. Nevertheless, the two AMH immunoassays are not using the same couple of antibodies and therefore not commutable and the definition of specific reference values and cut-point remains necessary.
抗苗勒管激素（AMH）的检测对于评估原发性卵巢功能不全、辅助生殖治疗的成功率以及支持多囊卵巢综合征的诊断具有重要意义。我们的研究表明，安世实验室的AMH免疫测定法具有出色的分析性能，并且与AMH Gen II测定法总体一致性良好。然而，这两种AMH免疫测定法使用的抗体对不同，因此不可互换，仍有必要定义特定的参考值和切点。
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