维也纳RNA网络服务。

The ViennaRNA web services.

作者信息

Gruber Andreas R, Bernhart Stephan H, Lorenz Ronny

机构信息

Biozentrum, University of Basel, Klingelbergstrasse 50-70, 4056, Basel, Switzerland,

出版信息

Methods Mol Biol. 2015;1269:307-26. doi: 10.1007/978-1-4939-2291-8_19.

DOI:10.1007/978-1-4939-2291-8_19

PMID:25577387

Abstract

The ViennaRNA package is a widely used collection of programs for thermodynamic RNA secondary structure prediction. Over the years, many additional tools have been developed building on the core programs of the package to also address issues related to noncoding RNA detection, RNA folding kinetics, or efficient sequence design considering RNA-RNA hybridizations. The ViennaRNA web services provide easy and user-friendly web access to these tools. This chapter describes how to use this online platform to perform tasks such as prediction of minimum free energy structures, prediction of RNA-RNA hybrids, or noncoding RNA detection. The ViennaRNA web services can be used free of charge and can be accessed via http://rna.tbi.univie.ac.at.

摘要

ViennaRNA软件包是一个广泛使用的程序集合，用于进行RNA二级结构的热力学预测。多年来，在该软件包核心程序的基础上又开发了许多其他工具，以解决与非编码RNA检测、RNA折叠动力学或考虑RNA - RNA杂交的高效序列设计相关的问题。ViennaRNA网络服务为这些工具提供了便捷且用户友好的网络访问方式。本章介绍如何使用这个在线平台来执行诸如预测最小自由能结构、预测RNA - RNA杂交体或非编码RNA检测等任务。ViennaRNA网络服务可免费使用，可通过http://rna.tbi.univie.ac.at访问。