Institute for Theoretical Chemistry, University of Vienna, Vienna, Austria.
Bioinformatics. 2012 Oct 1;28(19):2530-1. doi: 10.1093/bioinformatics/bts466. Epub 2012 Jul 24.
While there are numerous programs that can predict RNA or DNA secondary structures, a program that predicts RNA/DNA hetero-dimers is still missing. The lack of easy to use tools for predicting their structure may be in part responsible for the small number of reports of biologically relevant RNA/DNA hetero-dimers.
We present here an extension to the widely used ViennaRNA Package (Lorenz et al., 2011) for the prediction of the structure of RNA/DNA hetero-dimers.
http://www.tbi.univie.ac.at/~ronny/RNA/vrna2.html
ronny@tbi.univie.ac.at, berni@bioinf.uni-leipzig.de
Supplementary data are available at Bioinformatics online.
虽然有许多程序可以预测 RNA 或 DNA 的二级结构，但仍然缺少可以预测 RNA/DNA 杂种二聚体的程序。缺乏易于使用的预测其结构的工具可能部分导致报告的具有生物学相关性的 RNA/DNA 杂种二聚体数量较少。
我们在此介绍了对广泛使用的 ViennaRNA 包（Lorenz 等人，2011）的扩展，用于预测 RNA/DNA 杂种二聚体的结构。
http://www.tbi.univie.ac.at/~ronny/RNA/vrna2.html
ronny@tbi.univie.ac.at，berni@bioinf.uni-leipzig.de
补充数据可在 Bioinformatics 在线获得。
