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[男性包皮环切术对中国降低尿路感染和泌尿生殖系统癌症的长期益处]

[Long-term benefit of male circumcision to the reduction of urinary tract infections and genitourinary cancers in China].

作者信息

Zhao Fu-jun, Li Philip S, Lü Nian-qing, Lee Richard, Peng Yi-feng, Cheng Feng, Li Zheng, Xu Hao-qin, Barone Mark, Goldstein Marc, Xia Shu-jia

机构信息

Department of Urology, Weil Cornell Medical College of Cornell University, New York, NY, USA.

出版信息

Zhonghua Nan Ke Xue. 2014 Nov;20(11):969-77.

PMID:25577830
Abstract

Increasingly accumulated results from randomized controlled trials and other clinical studies have demonstrated that male circumcision reduces the risks of acquisition and transmission of HIV, HPV, HSV-2, and other sexually transmitted infections, and thus has a potential role in preventing cervical cancer, penile cancer and prostate cancer. The prevalence of male circumcision in China is currently less than 5%. The clinical evaluation studies and randomized controlled trials of the Shang Ring device showed excellent safety profiles, extremely high acceptability, and satisfaction among the participants and service providers in Africa and China. Given the recent recommendations by the World Health Organization and the Joint United Nations Program on HIV/AIDS (UNAIDS), voluntary medical male circumcision should be promoted in China at the national level as an important alternative intervention to reduce reproductive tract infections and prevent both males and females from reproductive tract cancers. More emphasis is required on the studies of the long-term health benefits of male circumcision in uro-andrology.

摘要

越来越多随机对照试验和其他临床研究的结果表明,男性包皮环切术可降低感染和传播艾滋病毒、人乳头瘤病毒、单纯疱疹病毒2型及其他性传播感染的风险,因此在预防宫颈癌、阴茎癌和前列腺癌方面具有潜在作用。目前中国男性包皮环切术的普及率低于5%。尚环装置的临床评估研究和随机对照试验表明,在非洲和中国,该装置安全性极佳,接受度极高,参与者和服务提供者满意度也很高。鉴于世界卫生组织和联合国艾滋病规划署(UNAIDS)最近的建议,中国应在国家层面推广自愿医学男性包皮环切术,将其作为减少生殖道感染、预防男性和女性生殖道癌症的重要替代干预措施。在泌尿男科领域,需要更加重视男性包皮环切术长期健康益处的研究。

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Zhonghua Nan Ke Xue. 2014 Nov;20(11):969-77.
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