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炎症性脱髓鞘性多发性神经病中的Gm单倍型

Gm haplotypes in inflammatory demyelinating polyneuropathies.

作者信息

Feeney D J, Pollard J D, McLeod J G, Stewart G J, De Lange G G

机构信息

Department of Medicine, University of Sydney, NSW, Australia.

出版信息

Ann Neurol. 1989 Dec;26(6):790-2. doi: 10.1002/ana.410260619.

Abstract

The possible association of Gm haplotypes with inflammatory neuropathies has been studied in 59 patients with Guillain-Barré syndrome and 55 patients with chronic inflammatory demyelinating polyradiculoneuropathy. The frequency of Gm haplotype 1,2,17;21 (or z,a,x;g) was significantly raised in the patients with Guillain-Barré syndrome. These findings provide further evidence for an association of chromosome 14 genes with inflammatory neuropathies.

摘要

研究了59例吉兰 - 巴雷综合征患者和55例慢性炎症性脱髓鞘性多发性神经根神经病患者中Gm单倍型与炎性神经病的可能关联。吉兰 - 巴雷综合征患者中Gm单倍型1,2,17;21(或z,a,x;g)的频率显著升高。这些发现为14号染色体基因与炎性神经病的关联提供了进一步的证据。

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