Are QTc interval changes after meal intake a reasonable method to prove assay sensitivity in thorough QT studies?

Hnatkova Katerina, Kowalski Donna, Keirns James J, van Gelderen E Marcel, Malik Marek

Imperial College, London, England.

Global Clinical Pharmacology and Exploratory Development, Astellas Pharma Global Development Inc., Northbrook, IL, USA.

J Electrocardiol. 2015 Mar-Apr;48(2):276-7. doi: 10.1016/j.jelectrocard.2015.01.005. Epub 2015 Jan 6.

Abstract

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