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指南:盆腔放射性疾病胃肠道症状的实际管理

Guidance: The practical management of the gastrointestinal symptoms of pelvic radiation disease.

作者信息

Andreyev H Jervoise N, Muls Ann C, Norton Christine, Ralph Charlotte, Watson Lorraine, Shaw Clare, Lindsay James O

机构信息

The GI and Nutrition Team , The Royal Marsden NHS Foundation Trust , London and Surrey , UK.

King's College London , London , UK.

出版信息

Frontline Gastroenterol. 2015 Jan;6(1):53-72. doi: 10.1136/flgastro-2014-100468. Epub 2014 Jun 17.

Abstract

BACKGROUND

A recent randomised trial suggested that an algorithmic approach to investigating and managing gastrointestinal symptoms of pelvic radiation disease (PRD) is beneficial and that specially trained nurses can manage patients as effectively as a gastroenterologist.

AIMS

The aim of the development and peer review of the guide was to make the algorithm used in the trial accessible to all levels of clinician.

METHODS

Experts who manage patients with PRD were asked to review the guide, rating each section for agreement with the recommended measures and suggesting amendments if necessary. Specific comments were discussed and incorporated as appropriate, and this process was repeated for a second round of review.

RESULTS

34 gastroenterologists, 10 nurses, 9 dietitians, 7 surgeons and 5 clinical oncologists participated in round one. Consensus (defined prospectively as 60% or more panellists selecting 'strongly agree' or 'agree') was reached for 27 of the original 28 sections in the guide, with a median of 75% of panellists agreeing with each section. 86% of panellists agreed that the guide was acceptable for publication or acceptable with minor revisions. 55 of the original 65 panellists participated in round two. 89% agreed it was acceptable for publication after the first revision. Further minor amendments were made in response to round two.

CONCLUSIONS

Development of the guide in response to feedback included ▸ improvement of occasional algorithmic steps ▸ a more user-friendly layout ▸ clearer timeframes for referral to other teams ▸ expansion of reference list ▸ addition of procedures to the appendix.

摘要

背景

最近一项随机试验表明,采用算法方法来调查和管理盆腔放射性疾病(PRD)的胃肠道症状是有益的,并且经过专门培训的护士在管理患者方面能与胃肠病专家一样有效。

目的

制定该指南并进行同行评审的目的是让各级临床医生都能使用试验中所采用的算法。

方法

邀请管理PRD患者的专家对该指南进行评审,对每个部分与推荐措施的一致性进行评分,并在必要时提出修改建议。对具体意见进行了讨论并酌情纳入,第二轮评审重复了这一过程。

结果

第一轮有34名胃肠病专家、10名护士、9名营养师、7名外科医生和5名临床肿瘤学家参与。指南最初的28个部分中有27个达成了共识(前瞻性定义为60%或更多的小组成员选择“强烈同意”或“同意”),各部分同意的小组成员中位数为75%。86%的小组成员认为该指南可以接受发表或稍作修改即可接受。最初的65名小组成员中有55名参与了第二轮评审。89%的人同意在第一次修订后可以接受发表。针对第二轮评审又进行了进一步的小修改。

结论

根据反馈意见制定该指南包括:改进偶尔的算法步骤;采用更便于用户使用的布局;明确转诊至其他团队的时间框架;扩充参考文献列表;在附录中增加操作流程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffe/5369554/ed3a3c7caed2/flgastro-2014-100468f01.jpg

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