Khan M A, Sen P C
Indian J Exp Biol. 1989 Jan;27(1):96-7.
Histamine receptors on the surface of E. histolytica could be demonstrated by histochemical method using three isolates of the protozoa grown and maintained in modified Boeck and Drbohlav's medium. Prior treatment of E. histolytica with cimetidine a H2 blocker, blocked the histamine uptake. Similar treatment with mepyramine maleate, a H1 blocker, did not prevent histamine uptake by the protozoa. It is postulated that E. histolytica has H2 receptors on its surface.
利用在改良的伯克和德尔博赫拉夫培养基中培养并维持的三种溶组织内阿米巴原虫分离株，通过组织化学方法可证明溶组织内阿米巴表面的组胺受体。用H2阻滞剂西咪替丁预先处理溶组织内阿米巴，可阻断组胺摄取。用H1阻滞剂马来酸氯苯那敏进行类似处理，并未阻止原虫摄取组胺。据推测，溶组织内阿米巴在其表面具有H2受体。
