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阿达木单抗治疗与克罗恩病相关的化脓性汗腺炎。

Adalimumab treatment for hidradenitis suppurativa associated with Crohn's disease.

作者信息

Diamantova Dominika, Lomickova Iva, Cetkovska Petra

机构信息

Dominka Diamantova, MD, Department of Dermatology and Venereology, Military Hospital, Sišilovo nam. 7, Olomouc, Czech Republic;

出版信息

Acta Dermatovenerol Croat. 2014;22(4):291-3.

Abstract

Hidradenitis suppurativa (HS) is a chronic, inflammatory disease characterized by recurring abscesses, nodules, and fistulas predominantly in the area of the groin and axillae. The association between HS and Crohn's disease (CD) has already been documented. We report on a case of a patient with CD associated HS, refractory to multiple local and systemic agents.A complete resolution of both diseases was finally achieved after treatment with adalimumab. Our case report supports the co-occurrence of both diseases and suggests that adalimumab approved for CD might also be a safe and effective therapeutic option in the treatment of HS.

摘要

化脓性汗腺炎(HS)是一种慢性炎症性疾病,其特征主要为腹股沟和腋窝区域反复出现脓肿、结节和瘘管。HS与克罗恩病(CD)之间的关联已有文献记载。我们报告了1例患有CD相关HS的患者,该患者对多种局部和全身用药均难治。在用阿达木单抗治疗后,两种疾病最终均完全缓解。我们的病例报告支持这两种疾病同时存在,并表明已获批用于CD的阿达木单抗在治疗HS时可能也是一种安全有效的治疗选择。

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