Bassas-Vila J, González Lama Y
Servei de Dermatologia, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, España.
Unidad de Enfermedad Inflamatoria Intestinal, Servicio de Gastroenterología y Hepatología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, España.
Actas Dermosifiliogr. 2016 Sep;107 Suppl 2:27-31. doi: 10.1016/S0001-7310(17)30006-6.
The first description of perianal fistulas and complications in Crohn disease was made 75 years ago by Penner and Crohn. Published studies have subsequently confirmed that perianal fistulas are the most common manifestations of fistulising Crohn disease. Hidradenitis suppurativa was described in 1854 by a French surgeon, Aristide Verneuil. It is a chronic, inflammatory, recurrent and debilitating disease of the pilosebaceous follicle, that usually manifests after puberty with deep, painful and inflamed lesions in the areas of the body with apocrine glands, usually the axillary, inguinal and anogenital regions. The differential diagnosis between hidradenitis suppurativa and Crohn disease can be challenging, especially when the disease is primarily perianal. When they occur simultaneously, hidradenitis suppurativa and Crohn disease show severe phenotypes and patients can respond to anti-tumour necrosis factor therapy, although adalimumab is currently the only treatment with demonstrated efficacy in hidradenitis suppurativa and Crohn disease. In addition, there is sometimes a need for different complementary surgical procedures.
75年前，彭纳（Penner）和克罗恩（Crohn）首次描述了克罗恩病中的肛周瘘管及其并发症。随后发表的研究证实，肛周瘘管是瘘管性克罗恩病最常见的表现。化脓性汗腺炎于1854年由法国外科医生阿里斯蒂德·韦尔纳伊（Aristide Verneuil）首次描述。它是一种毛囊皮脂腺的慢性、炎症性、复发性且使人衰弱的疾病，通常在青春期后出现，在身体有顶泌汗腺的部位出现深部、疼痛且发炎的病变，通常是腋窝、腹股沟和肛门生殖器区域。化脓性汗腺炎和克罗恩病之间的鉴别诊断可能具有挑战性，尤其是当疾病主要累及肛周时。当它们同时发生时，化脓性汗腺炎和克罗恩病会表现出严重的表型，患者可能对抗肿瘤坏死因子治疗有反应，尽管阿达木单抗是目前唯一在化脓性汗腺炎和克罗恩病中显示出疗效的治疗方法。此外，有时还需要不同的辅助手术程序。
