Zhao De-Wei, Yu Xiao-Bing
Department of Orthopaedics, Zhongshan Hospital of Dalian University, Dalian, China.
Department of Orthopaedics, Zhongshan Hospital of Dalian University, Dalian, China.
J Surg Res. 2015 Apr;194(2):614-621. doi: 10.1016/j.jss.2014.12.007. Epub 2014 Dec 11.
The objective of this study was to explore the therapeutic effect of core decompression on different hemodynamics changes associated with osteonecrosis of the femoral head (ONFH).
A total of 67 patients with 76 hips suffering from ONFH (Arco stage I-IIC) received core decompression surgical procedure. Radiographic, magnetic resonance imaging, and digital subtraction angiography examinations were performed before operation. Radiographic and magnetic resonance imaging follow-ups were also performed after 12, 24, and 60 mo of operation. Clinical follow-ups were performed using the Harris Hip Score (HHS) for an average period of 5 y postoperation.
The mean follow-up time ranged from 2-8 y with an average of 5 y. Two hips were lost during follow-up. Successful clinical efficacy (HHS ≥80) was achieved in 91.9% (68/74) of the hips. Six hips had conversion to total hip arthroplasty (THA), one hip had venous stasis, and five hips had both vein stasis and artery blood supply insufficiency. The mean HHS for the patients who did not have conversion to THA improved from 65 ± 3.5 to 89 ± 3.6 (mean ± standard deviation). Twenty-six stage I hips (100%), 22 of 23 stage IIA hips (95.7%), 13 of 15 stage IIB hips (86.7%), and 8 of 10 stage IIC hips (80%) had successful outcomes with no surgical complications. Kaplan-Meier survival analysis showed that 8-y survival rate was significantly different between stage I and stage IIC (THA as an end point; P < 0.001).
In patients with early-stage ONFH resulted from only venous stasis, core decompression led to a significant improvement in HHS and 8-y survival rate. However, the long-term efficacy for ONFH associated with artery blood supply insufficiency was not encouraging. Therefore, preoperative digital subtraction angiography is necessary before performing core decompression.
本研究的目的是探讨髓芯减压术对股骨头坏死(ONFH)相关的不同血流动力学变化的治疗效果。
共有67例76髋ONFH患者(Arco分期I - IIC期)接受了髓芯减压手术。术前进行了X线、磁共振成像和数字减影血管造影检查。术后12、24和60个月也进行了X线和磁共振成像随访。采用Harris髋关节评分(HHS)进行临床随访,平均随访时间为术后5年。
平均随访时间为2 - 8年,平均5年。随访期间有2髋失访。91.9%(68/74)的髋关节临床疗效成功(HHS≥80)。6髋行全髋关节置换术(THA),1髋有静脉淤滞,5髋既有静脉淤滞又有动脉血供不足。未行THA转换的患者平均HHS从65±3.5提高到89±3.6(平均值±标准差)。26例I期髋关节(100%)、23例IIA期髋关节中的22例(95.7%)、15例IIB期髋关节中的13例(86.7%)和10例IIC期髋关节中的8例(80%)取得了成功的结果,且无手术并发症。Kaplan - Meier生存分析显示,I期和IIC期的8年生存率有显著差异(以THA为终点;P < 0.001)。
对于仅由静脉淤滞导致的早期ONFH患者,髓芯减压术可显著提高HHS和8年生存率。然而,与动脉血供不足相关的ONFH的长期疗效并不理想。因此,在进行髓芯减压术前,术前数字减影血管造影是必要的。