Forner-Cordero I, Szolnoky G, Forner-Cordero A, Kemény L
Lymphedema Unit, Rehabilitation Department. University Hospital La Fe, Valencia, Spain.
Clin Obes. 2012 Jun;2(3-4):86-95. doi: 10.1111/j.1758-8111.2012.00045.x. Epub 2012 Aug 3.
Lipedema is a disproportionate, symmetrical fatty swelling characterized by pain and bruising existing almost exclusively among women. We undertook a systematic review of the available literature about lipedema, given the lack of knowledge and little evidence about this disorder especially among obesity experts. Diagnosis of lipedema is usually based on clinical features. Symmetrical edema in the lower limbs with fatty deposits located to hips and thighs usually appears at puberty and often affects several members of the same family. Main disorders considered for differential diagnosis are lymphedema, obesity, lipohypertrophy and phlebedema. Treatment protocols comprise conservative (decongestive lymphatic therapy) and surgical (liposuction) approaches. Early diagnosis and treatment are mandatory for this disorder otherwise gradual enlargement of fatty deposition causes impaired mobility and further comorbidities like arthrosis and lymphatic insufficiency.
脂肪性水肿是一种不成比例的、对称性的脂肪肿胀，其特征为疼痛和瘀伤，几乎仅见于女性。鉴于对这种疾病缺乏了解且证据稀少，尤其是在肥胖症专家中，我们对有关脂肪性水肿的现有文献进行了系统综述。脂肪性水肿的诊断通常基于临床特征。下肢对称性水肿伴脂肪沉积于臀部和大腿，通常在青春期出现，且常影响同一家族的多名成员。鉴别诊断时需考虑的主要疾病有淋巴水肿、肥胖症、脂肪增生和静脉性水肿。治疗方案包括保守治疗（充血性淋巴治疗）和手术治疗（抽脂）。对于这种疾病，早期诊断和治疗至关重要，否则脂肪沉积的逐渐扩大将导致活动能力受损，并引发诸如关节炎和淋巴功能不全等更多合并症。
