Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK).
Angew Chem Int Ed Engl. 2015 Mar 9;54(11):3449-64. doi: 10.1002/anie.201410744. Epub 2015 Jan 13.
Organic synthesis is changing; in a world where budgets are constrained and the environmental impacts of practice are scrutinized, it is increasingly recognized that the efficient use of human resource is just as important as material use. New technologies and machines have found use as methods for transforming the way we work, addressing these issues encountered in research laboratories by enabling chemists to adopt a more holistic systems approach in their work. Modern developments in this area promote a multi-disciplinary approach and work is more efficient as a result. This Review focuses on the concepts, procedures and methods that have far-reaching implications in the chemistry world. Technologies have been grouped as topics of opportunity and their recent applications in innovative research laboratories are described.
有机合成正在发生变化;在预算有限且实践对环境影响受到严格审查的世界中,人们越来越认识到,有效利用人力资源与物质利用同样重要。新技术和机器已被用作改变我们工作方式的方法,通过使化学家在工作中采用更全面的系统方法,解决研究实验室中遇到的这些问题。该领域的现代发展促进了多学科方法,从而提高了工作效率。本文重点介绍了在化学界具有深远影响的概念、程序和方法。根据技术的应用,将其分为若干专题,并描述了它们在创新研究实验室中的最新应用。