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一种超微型热中子监测器在基于加速器的中子俘获治疗照射场研究中的应用。

Application of an ultraminiature thermal neutron monitor for irradiation field study of accelerator-based neutron capture therapy.

作者信息

Ishikawa Masayori, Tanaka Kenichi, Endo Satrou, Hoshi Masaharu

机构信息

Department of Medical Physics and Engineering, Graduate School of Medicine, Hokkaido University, N-15 W-7 Kita-ku, Sapporo Hokkaido, 060-8638, Japan

Center of Medical Education, Sapporo Medical University, S-1 W-16 Chuo-ku, Sapporo Hokkaido, 060-8543, Japan.

出版信息

J Radiat Res. 2015 Mar;56(2):391-6. doi: 10.1093/jrr/rru112. Epub 2015 Jan 14.

DOI:10.1093/jrr/rru112
PMID:25589504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4380057/
Abstract

Phantom experiments to evaluate thermal neutron flux distribution were performed using the Scintillator with Optical Fiber (SOF) detector, which was developed as a thermal neutron monitor during boron neutron capture therapy (BNCT) irradiation. Compared with the gold wire activation method and Monte Carlo N-particle (MCNP) calculations, it was confirmed that the SOF detector is capable of measuring thermal neutron flux as low as 10(5) n/cm(2)/s with sufficient accuracy. The SOF detector will be useful for phantom experiments with BNCT neutron fields from low-current accelerator-based neutron sources.

摘要

使用带有光纤的闪烁体(SOF)探测器进行了评估热中子通量分布的模体实验,该探测器是作为硼中子俘获疗法(BNCT)照射期间的热中子监测器而开发的。与金线活化法和蒙特卡罗N粒子(MCNP)计算相比,证实了SOF探测器能够以足够的精度测量低至10(5) n/cm(2)/s的热中子通量。SOF探测器将有助于使用基于低电流加速器的中子源进行BNCT中子场的模体实验。

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Application of an ultraminiature thermal neutron monitor for irradiation field study of accelerator-based neutron capture therapy.一种超微型热中子监测器在基于加速器的中子俘获治疗照射场研究中的应用。
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本文引用的文献

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Implantable self-powered detector for on-line determination of neutron flux in patients during NCT treatment.用于在硼中子俘获治疗(NCT)期间在线测定患者体内中子通量的可植入自供电探测器。
Appl Radiat Isot. 2004 Nov;61(5):1033-7. doi: 10.1016/j.apradiso.2004.05.041.
2
Development of real-time thermal neutron monitor using boron-loaded plastic scintillator with optical fiber for boron neutron capture therapy.用于硼中子俘获治疗的含硼塑料闪烁体与光纤实时热中子监测器的研制。
Appl Radiat Isot. 2004 Nov;61(5):775-9. doi: 10.1016/j.apradiso.2004.05.053.
3
A Monte Carlo dosimetry-based evaluation of the 7Li(p,n)7Be reaction near threshold for accelerator boron neutron capture therapy.
基于蒙特卡罗剂量学的加速器硼中子俘获治疗阈值附近7Li(p,n)7Be反应评估。
Med Phys. 2000 Jan;27(1):192-202. doi: 10.1118/1.598884.
4
Fission converter and metal-oxide-semiconductor field effect transistor study of thermal neutron flux distribution in an epithermal neutron therapy beam.
Med Phys. 1999 Sep;26(9):1989-94. doi: 10.1118/1.598703.