Dong Yonghui, Guella Graziano, Mattivi Fulvio, Franceschi Pietro
Biostatistics and Data Management, Research and Innovation Centre-Fondazione Edmund Mach, S. Michele all'Adige, TN, Italy.
J Am Soc Mass Spectrom. 2015 Mar;26(3):386-9. doi: 10.1007/s13361-014-1065-y. Epub 2015 Jan 17.
A significant production of gas-phase dicarboxylate dianions has been observed in standard ESI and DESI during the analysis of small organic dicarboxylic acids under moderate or highly alkaline conditions. In ESI, this can be attributed to an excess of hydroxyl ions (OH(-)) which favor the formation of an high amount of dianions in solution, contemporarily trapping the potential counter ions during the ESI process. The results obtained in DESI highlight the role of the surface in trapping the counter-ions during desorption process and determining the ultimate nature of the observed gas-phase ions.
在对小分子有机二羧酸进行分析时，于中等或高碱性条件下的标准电喷雾电离（ESI）和解吸电喷雾电离（DESI）过程中，已观察到大量气相二羧酸二价阴离子的产生。在ESI中，这可归因于过量的氢氧根离子（OH(-)），其有利于在溶液中形成大量二价阴离子，同时在ESI过程中捕获潜在的抗衡离子。DESI所获得的结果突出了表面在解吸过程中捕获抗衡离子以及确定所观察到的气相离子最终性质方面的作用。
