Guzzini F, Cozzi C, Cortese F, Gasparini P, Neri V, Pace L
U.S.S.L. 9 Divisione di Medicina II, Ospedale di Saronno, Varese, Italy.
Tumori. 1989 Dec 31;75(6):634-6. doi: 10.1177/030089168907500625.
We describe two patients with lung carcinoma in whom adrenal glands were the sole site of tumor relapse, revealed by the appearance of Addison's disease. Both patients showed bilateral adrenal masses on US and/or CAT scans and received hormone replacement therapy, with rapid improvement of their general conditions. One of them, with small-cell carcinoma, could also be treated with further chemotherapy and achieved a second remission. Therefore, we stress that patients with lung carcinoma should be periodically screened for adrenal deposits by US or CAT and undergo prophylactic steroid maintenance whenever metastatic involvement of the glands is detected.
我们描述了两名肺癌患者，其肾上腺是肿瘤复发的唯一部位，这是由艾迪生病的表现揭示的。两名患者的超声和/或计算机断层扫描（CAT）均显示双侧肾上腺肿块，并接受了激素替代治疗，全身状况迅速改善。其中一名患有小细胞癌的患者，还可以接受进一步的化疗，并实现了二次缓解。因此，我们强调，肺癌患者应定期通过超声或CAT筛查肾上腺沉积物，一旦检测到肾上腺有转移累及，应进行预防性类固醇维持治疗。
