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Differences in the erythropoiesis-hepcidin-iron store axis between hemoglobin H disease and β-thalassemia intermedia.

作者信息

Origa Raffaella, Cazzola Mario, Mereu Elisabetta, Danjou Fabrice, Barella Susanna, Giagu Nicolina, Galanello Renzo, Swinkels Dorine W

机构信息

Ospedale Microcitemico-Department of Public Health, Clinical and Molecular Medicine, University of Cagliari, Italy.

Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, and Department of Molecular Medicine, University of Pavia, Italy.

出版信息

Haematologica. 2015 May;100(5):e169-71. doi: 10.3324/haematol.2014.115733. Epub 2015 Jan 16.

DOI:10.3324/haematol.2014.115733
PMID:25596269
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4420223/
Abstract
摘要

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本文引用的文献

1
Identification of erythroferrone as an erythroid regulator of iron metabolism.鉴定红系铁调素为铁代谢的红系调节因子。
Nat Genet. 2014 Jul;46(7):678-84. doi: 10.1038/ng.2996. Epub 2014 Jun 1.
2
Hepcidin in human iron disorders: diagnostic implications.人铁代谢紊乱中的铁调素：诊断意义。
Clin Chem. 2011 Dec;57(12):1650-69. doi: 10.1373/clinchem.2009.140053. Epub 2011 Oct 11.
3
Serum hepcidin: reference ranges and biochemical correlates in the general population.血清铁调素：普通人群的参考范围和生化相关性。
Blood. 2011 Jun 23;117(25):e218-25. doi: 10.1182/blood-2011-02-337907. Epub 2011 Apr 28.
4
Immunochemical and mass-spectrometry-based serum hepcidin assays for iron metabolism disorders.基于免疫化学和质谱的血清铁调素检测在铁代谢紊乱中的应用。
Clin Chem. 2010 Oct;56(10):1570-9. doi: 10.1373/clinchem.2010.149187. Epub 2010 Aug 25.
5
Hb H disease: clinical course and disease modifiers.Hb H 病：临床病程和疾病修饰因子。
Hematology Am Soc Hematol Educ Program. 2009:26-34. doi: 10.1182/asheducation-2009.1.26.
6
Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells.在小鼠和人类细胞中鉴定TWSG1作为铁调素表达的第二种新型红细胞调节因子。
Blood. 2009 Jul 2;114(1):181-6. doi: 10.1182/blood-2008-12-195503. Epub 2009 May 4.
7
High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin.地中海贫血中高水平的生长分化因子15抑制铁调节蛋白铁调素的表达。
Nat Med. 2007 Sep;13(9):1096-101. doi: 10.1038/nm1629. Epub 2007 Aug 26.
8
Liver iron concentrations and urinary hepcidin in beta-thalassemia.β地中海贫血患者的肝脏铁浓度和尿铁调素
Haematologica. 2007 May;92(5):583-8. doi: 10.3324/haematol.10842.
9
Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin.β地中海贫血中无效造血的特征是，通过铁调素下调和铁转运蛋白上调介导的铁吸收增加。
Blood. 2007 Jun 1;109(11):5027-35. doi: 10.1182/blood-2006-09-048868. Epub 2007 Feb 13.
10
Hepcidin in iron overload disorders.铁过载疾病中的铁调素
Blood. 2005 May 15;105(10):4103-5. doi: 10.1182/blood-2004-12-4844. Epub 2005 Jan 25.