[超声引导下甲状腺微小结节粗针活检、粗针吸取及细针吸取的疗效与局限性评估]

[Evaluation of the efficacy and the limitation of ultrasound-guided core-needle biopsy, core-needle aspiration and fine-needle aspiration in micro-nodules of thyroid].

作者信息

Zhang Shaohang, Niu Lijuan

机构信息

Department of Diagnostic Imaging, Cancer Hospital, Chinese Academy of Sciences, Peking Union Medical College, Beijing 100021, China.

Department of Diagnostic Imaging, Cancer Hospital, Chinese Academy of Sciences, Peking Union Medical College, Beijing 100021, China. Email:

出版信息

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2014 Nov;49(11):893-6.

PMID:25598366

Abstract

OBJECTIVE

To evaluate the efficacy and the limitation of ultrasound-guided core-needle biopsy, ultrasound-guided core-needle aspiration and ultrasound-guided fine-needle aspiration in micro-nodules of thyroid.

METHODS

A retrospective was performed in 92 patients with suspectable malignent micro-nodules in thyroid. Of them, 52 patients underwent US-CNB and US-FNA and 40 patients underwent US-CNA and US-FNA. The diagnoses for the micro-nodules were identified by histopathlogical examination after surgery.

RESULT

Among 52 cases with both US-CNB and US-FNA, 41 got nondiagnostic US-CNB and 11 cases successfully got the correct diagnoses of US-CNB; 6 cases got the incorrect diagnosis of US-FNA and 46 cases got the correct diagnosis of US-FNA. Of 40 cases with US-CNA and US-FNA, unsatisfactory specimen of US-CNA occurred in 14 cases and satisfactory specimen of US-CNA were got in 26 cases; unsatisfactory specimen of US-FNA occurred in 4 cases and satisfactory specimen of US-FNA. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of US-FNA in 92 cases for the diagnosis of malignancy were 93.4%, 86.7%, 97.3%, 72.2% and 92.3%, respectively.

CONCLUSIONS

US-FNA is the most valuable method for the diagnosis of suspectable malignent micro-nodules in thyroid before operation.

摘要

目的

评估超声引导下粗针活检、超声引导下粗针抽吸及超声引导下细针抽吸在甲状腺微小结节中的有效性及局限性。

方法

对92例疑似甲状腺恶性微小结节患者进行回顾性研究。其中，52例患者接受了超声引导下粗针活检（US-CNB）和超声引导下细针抽吸（US-FNA），40例患者接受了超声引导下粗针抽吸（US-CNA）和超声引导下细针抽吸（US-FNA）。术后通过组织病理学检查确定微小结节的诊断。

结果

在52例同时接受US-CNB和US-FNA的患者中，41例US-CNB诊断未明确，11例US-CNB成功获得正确诊断；6例US-FNA诊断错误，46例US-FNA诊断正确。在40例接受US-CNA和US-FNA的患者中，14例US-CNA标本不满意，26例US-CNA标本满意；4例US-FNA标本不满意，US-FNA标本满意。92例患者中，US-FNA诊断恶性肿瘤的敏感性、特异性、阳性预测值、阴性预测值及准确性分别为93.4%、86.7%、97.3%、72.2%和92.3%。