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[一种罕见的肺部肿瘤:肺母细胞瘤。附病例报告及文献复习]

[A rare pulmonary tumor: pneumoblastoma. Apropos of a case and review of the literature].

作者信息

Giron J, Eynius F, Joffre P, Senac J P, Marty-Ané C, Mary H, Baldet P

机构信息

Service de Radiologie, Hôpital St-Charles, Montpellier.

出版信息

J Radiol. 1989 Dec;70(12):725-9.

PMID:2559982
Abstract

A case of pneumoblastoma concerning a 33 year old man, incidentally discovered on a systematic chest X Ray, is reported. The radiologic findings include a voluminous and peripherical mass with necrotic zones. The pathologic findings in optic microscopy and the special technics consist in the three cellular contingents which form the pneumoblastoma: clusters of indifferentiated cells, epithelial cells and spindle cells. All the features show clearly a blastomatic character very similar to a foetal lung which allows to differentiate the pulmonary blastoma from carcinosarcoma. The authors, through a review of the literature, demonstrate the rarity (less than 100 cases reported), the malignant evolution which metastasis and the age (strong majority of adults) which characterize this pathology.

摘要

报告了一例33岁男性的肺母细胞瘤病例,该病例在系统性胸部X光检查中偶然发现。放射学检查结果包括一个体积较大的外周肿块,伴有坏死区域。光学显微镜和特殊技术下的病理检查结果显示,肺母细胞瘤由三种细胞成分组成:未分化细胞簇、上皮细胞和梭形细胞。所有特征均清晰显示出与胎儿肺非常相似的母细胞特征,这有助于将肺母细胞瘤与癌肉瘤区分开来。作者通过文献回顾,证明了这种病理特征的罕见性(报道病例少于100例)、具有转移特性的恶性进展以及发病年龄(绝大多数为成年人)。

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