Wicks Eleanor C, Menezes Leon J, Elliott Perry M
The Heart Hospital, 16-18 Westmoreland Street, London, W1G 8PH, UK.
Expert Rev Cardiovasc Ther. 2015 Feb;13(2):223-36. doi: 10.1586/14779072.2015.1001367.
Cardiac sarcoid is a potentially fatal condition that presents with a wide range of clinical manifestations including conduction abnormalities, tachyarrhythmias, congestive heart failure, cardiomyopathy and sudden cardiac death. Small observational registries and non-comparative studies have described clinical evidence of cardiac involvement in 5% of patients with systemic sarcoid, yet autopsy studies suggest prevalence as high as 79%. This suggests that cardiac sarcoidosis (CS) is underdiagnosed in everyday clinical practice. The scarcity of data and lack of consensus on the most appropriate methods for detecting, monitoring and treating CS presents a significant diagnostic and therapeutic challenge. This review explores the potential impact of novel strategies, including multimodality imaging, on the diagnostic accuracy for detecting CS and treatment.
心脏结节病是一种潜在的致命疾病，临床表现广泛，包括传导异常、快速性心律失常、充血性心力衰竭、心肌病和心源性猝死。小型观察性登记研究和非对照研究表明，5%的系统性结节病患者有心脏受累的临床证据，但尸检研究显示患病率高达79%。这表明在日常临床实践中，心脏结节病（CS）的诊断不足。关于检测、监测和治疗CS的最合适方法的数据稀缺且缺乏共识，这带来了重大的诊断和治疗挑战。本综述探讨了包括多模态成像在内的新策略对CS检测诊断准确性和治疗的潜在影响。
