†Osaka Prefectural Institute of Public Health, 1-3-69 Nakamichi, Higashinari-ku, Osaka 537-0025, Japan.
‡Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
J Agric Food Chem. 2015 Jun 3;63(21):5141-5. doi: 10.1021/jf505254y. Epub 2015 Jan 28.
A monitoring plan of residual antibiotics in food of animal origin was conducted in Vietnam from 2012 to 2013. Meat samples were collected from slaughterhouses and retail stores in Ho Chi Minh City and Nha Trang. A total of 28 antibiotics were analyzed using a LC-MS/MS screening method. Sulfonamides, fluoroquinolones, and tilmicosin were detected in some of the samples. Sulfaclozine and fluoroquinolones were mainly detected in chicken samples, and sulfamethazine was mainly detected in pork samples. High levels of sulfonamide residues, ranging between 2500 and 2700 μg/kg sulfaclozine and between 1300 and 3600 μg/kg sulfamethazine, were present in two chicken and three pork samples, respectively. Tilmicosin was detected at ranges of 150-450 μg/kg in 10 chicken samples. Positive percentages were 17.3, 8.8, and 7.4% for chicken, pork, and beef, respectively, for an average of 11.9%. The results suggest an appropriate withdrawal period after drug administration had not been observed in some livestock.
2012 年至 2013 年，越南开展了一项动物源食品中残留抗生素的监测计划。从胡志明市和芽庄的屠宰场和零售店采集了肉样。使用 LC-MS/MS 筛选方法分析了总共 28 种抗生素。在一些样本中检测到磺胺类药物、氟喹诺酮类药物和替米考星。磺胺类药物和氟喹诺酮类药物主要在鸡肉样品中检出，磺胺甲噁唑主要在猪肉样品中检出。在两个鸡肉和三个猪肉样品中，磺胺类药物残留水平较高，磺胺氯哒嗪在 2500 至 2700μg/kg 之间，磺胺甲噁唑在 1300 至 3600μg/kg 之间。在 10 个鸡肉样品中检测到替米考星的浓度范围为 150-450μg/kg。鸡肉、猪肉和牛肉的阳性率分别为 17.3%、8.8%和 7.4%，平均为 11.9%。结果表明，一些牲畜在用药后没有遵守适当的停药期。
