Dawson Heather, Kirsch Richard, Driman David K, Messenger David E, Assarzadegan Naziheh, Riddell Robert H
Department of Pathology and Laboratory Medicine, Mount Sinai Hospital and University of Toronto , Toronto, ON , Canada ; Clinical Pathology Division, Institute of Pathology, University of Bern , Bern , Switzerland.
Department of Pathology and Laboratory Medicine, Mount Sinai Hospital and University of Toronto , Toronto, ON , Canada.
Front Oncol. 2015 Jan 5;4:354. doi: 10.3389/fonc.2014.00354. eCollection 2014.
Venous invasion (VI) is a well-established independent prognostic indicator in colorectal cancer (CRC). Its accurate detection is particularly important in stage II CRC as it may influence the decision to administer adjuvant therapy. The Royal College of Pathologists (RCPath) of the United Kingdom state that VI should be detected in at least 30% of CRC resection specimens. However, our experience in Ontario, Canada suggests that this (conservative) benchmark is rarely met. This article highlights the "Ontario experience" with respect to VI reporting and the key role that careful morphologic assessment, elastin staining and knowledge transfer has played in improving VI detection provincially and beyond.
静脉侵犯（VI）是结直肠癌（CRC）中公认的独立预后指标。在II期CRC中准确检测VI尤为重要，因为它可能会影响辅助治疗的决策。英国皇家病理学家学院（RCPath）指出，至少30%的CRC切除标本应检测到VI。然而，我们在加拿大安大略省的经验表明，这一（保守的）基准很少能达到。本文重点介绍了安大略省在VI报告方面的“经验”，以及仔细的形态学评估、弹性蛋白染色和知识转移在全省及其他地区改善VI检测方面所发挥的关键作用。
