Ding Ningning, Mao Yousheng
Department of Thoracic Surgery, Cancer Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100021, China.
Zhongguo Fei Ai Za Zhi. 2015 Jan;18(1):34-41. doi: 10.3779/j.issn.1009-3419.2015.01.06.
Lung cancer ranks the first position in morbidity and mortality among all malignances in China. Non-small cell lung cancer (NSCLC) accounts for nearly 80% of all lung malignancies. Surgical resection is still the current major treatment method for early stage NSCLC. Lymph node stages together with the extent of lymph node dissection directly affect the prognosis. The site of primary lung carcinoma may affect the route and status of lymph node metastasis. Up to now, anatomical lobectomy and mediastinal lymph node dissection is deemed to be the standard surgical treatment for NSCLC. However, it is still controversial in the extent of lymph node dissection for T1 NSCLC. More and more surgeons intend to perform selective mediastinal lymph node dissection instead of complete mediastinal lymph node dissection for T1 NSCLC in recent years.
在中国,肺癌的发病率和死亡率在所有恶性肿瘤中位居首位。非小细胞肺癌(NSCLC)占所有肺部恶性肿瘤的近80%。手术切除仍是目前早期NSCLC的主要治疗方法。淋巴结分期以及淋巴结清扫范围直接影响预后。原发性肺癌的部位可能影响淋巴结转移的途径和状态。迄今为止,解剖性肺叶切除术和纵隔淋巴结清扫术被认为是NSCLC的标准外科治疗方法。然而,对于T1期NSCLC的淋巴结清扫范围仍存在争议。近年来,越来越多的外科医生倾向于对T1期NSCLC行选择性纵隔淋巴结清扫而非完全性纵隔淋巴结清扫。