社区获得性尿路病原体在全科医疗中的抗菌药物敏感性
Antimicrobial susceptibility of community-acquired uropathogens in general practice.
作者信息
Keah Sh, Wee Ec, Chng Ks, Keah Kc
机构信息
Keah Say Hien ,FRACGP, AM, Family Physician, Elizabeth Medical Centre Sdn Bhd, 1-14, Jalan Arab, 84000 Muar, Johor, Malaysia Tel: 06-9535335, Email:
Wee Eng Chye ,FRACGP, Family Physician, Woo Dispensary, 4, Jalan Gambir 1, Bandar Baru Bukit Gambir, 84800 Muar, Johor. Tel: 06-9761041. Email:
出版信息
Malays Fam Physician. 2007 Aug 31;2(2):64-9. eCollection 2007.
Antibiotic resistance of urinary tract pathogens has increased worldwide. The purpose of this study is to provide information regarding local resistance pattern of urinary pathogens to the commonly used antibiotics. One hundred and seventeen cases of community-acquired urinary tract infections were studied. The most common group of patients was the uncomplicated acute cystitis in women. E. coli was the most common isolate. Overall, antimicrobial susceptibility test on the organisms isolated showed a resistance of 63.0% to ampicillin, 40.1% to sulfamethoxazole-trimethoprim (S-T), 14.3% to pipemidic acid, 8.6% to norfloxacin, 3.8% to cephalexin, 3.7% to amoxicillin-clavulanate, 1.0% to cefuroxime, and 1.0% to fosfomycin. Three out of five patients on ampicillin as well as two out of five patients on S-T were likely to be inadequately treated.
全球范围内，泌尿道病原体的抗生素耐药性有所增加。本研究的目的是提供有关泌尿道病原体对常用抗生素的局部耐药模式的信息。对117例社区获得性泌尿道感染病例进行了研究。最常见的患者群体是女性单纯性急性膀胱炎。大肠埃希菌是最常见的分离菌株。总体而言，对分离出的病原体进行的抗菌药敏试验显示，对氨苄西林的耐药率为63.0%，对磺胺甲恶唑-甲氧苄啶（S-T）的耐药率为40.1%，对吡哌酸的耐药率为14.3%，对诺氟沙星的耐药率为8.6%，对头孢氨苄的耐药率为3.8%，对阿莫西林-克拉维酸的耐药率为3.7%，对头孢呋辛的耐药率为1.0%，对磷霉素的耐药率为1.0%。使用氨苄西林治疗的五名患者中有三名以及使用S-T治疗的五名患者中有两名可能治疗不充分。
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