Johnson James R, Murray Andrew C, Kuskowski Michael A, Schubert Sören, Prère Marie-Francoise, Picard Bertrand, Colodner Raul, Raz Raul
Infectious Diseases (111F), Minneapolis VA Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA.
Emerg Infect Dis. 2005 Jan;11(1):141-5. doi: 10.3201/eid1101.040418.
Among 1,102 recent Escherichia coli clinical isolates, clonal group A was identified in 17 of 20 (U.S. and non-U.S.) geographic locales, mainly among U.S. isolates (9% vs. 3%; p < 0.001) and those resistant to trimethoprim-sulfamethoxazole (10% vs. 1.7%; p < 0.001). The extensive antimicrobial resistance and virulence profiles of clonal group A may underlie its recent widespread emergence.
在1102株近期的大肠杆菌临床分离株中，克隆群A在20个（美国和非美国）地理区域中的17个区域被鉴定出来，主要集中在美国的分离株中（9%对3%；p<0.001）以及对甲氧苄啶-磺胺甲恶唑耐药的分离株中（10%对1.7%；p<0.001）。克隆群A广泛的抗菌药物耐药性和毒力特征可能是其近期广泛出现的原因。
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