Loh Ky, Agarwal P
Malays Fam Physician. 2010 Apr 30;5(1):6-8. eCollection 2010.
A corneal ulcer caused by infection is one of the major causes of blindness worldwide. One of the recent health concerns is the increasing incidence of corneal ulcers associated with contact lens user especially if the users fail to follow specific instruction in using their contact lenses. Risk factors associated with increased risk of contact lens related corneal ulcers are: overnight wear, long duration of continuous wear, lower socio-economic classes, smoking, dry eye and poor hygiene. The presenting symptoms of contact lens related corneal ulcers include eye discomfort, foreign body sensation and lacrimation. More serious symptoms are redness (especially circum-corneal injection), severe pain, photophobia, eye discharge and blurring of vision. The diagnosis is established by a thorough slit lamp microscopic examination with fluorescein staining and corneal scraping for Gram stain and culture of the infective organism. Delay in diagnosing and treatment can cause permanent blindness, therefore an early referral to ophthalmologist and commencing of antimicrobial therapy can prevent visual loss.
由感染引起的角膜溃疡是全球失明的主要原因之一。近期的健康问题之一是与隐形眼镜使用者相关的角膜溃疡发病率不断上升,尤其是当使用者未遵循使用隐形眼镜的特定说明时。与隐形眼镜相关角膜溃疡风险增加相关的危险因素包括:过夜佩戴、连续佩戴时间长、社会经济阶层较低、吸烟、干眼和卫生条件差。隐形眼镜相关角膜溃疡的表现症状包括眼部不适、异物感和流泪。更严重的症状是眼红(尤其是角膜周围充血)、剧痛、畏光、眼部分泌物和视力模糊。通过使用荧光素染色进行全面的裂隙灯显微镜检查以及对感染性生物体进行角膜刮片革兰氏染色和培养来确诊。诊断和治疗的延迟可能导致永久性失明,因此尽早转诊至眼科医生并开始抗菌治疗可预防视力丧失。