一例因他克莫司导致进行性神经障碍的肾移植患者病例报告。
A Case Report of a Renal Transplant Patient with Progressive Neurological Disorder due to Tacrolimus.
作者信息
Sagiroglu Tamer, Meydan Burhan
机构信息
Kartal Dr. Lütfü Kırdar Training and Research Hospital, Transplantation Center, İstanbul, Turkey.
Süreyyapaşa Pulmoner Disease and Thorasic Surgery Education And Research Hospital, Department of Anesthesiology, İstanbul, Turkey.
出版信息
Eurasian J Med. 2009 Dec;41(3):200-1.
Neurological complications of tacrolimus are usually mild (tremors, paresthesia, myalgia), however, serious complications that result in encephalopathy, convulsions and coma can be seen. Serious complications are more frequently reported following liver transplants and lungs transplants than renal transplants and are typically seen when tacrolimus concentrations exceed the 15 ng/L therapeutic limit. In this article we presented our case of a renal allograft receiver with nausea, dizziness and fatigue complaints.
他克莫司的神经并发症通常较轻（震颤、感觉异常、肌痛），然而，也可见导致脑病、惊厥和昏迷的严重并发症。肝移植和肺移植后比肾移植更常报告严重并发症，并且通常在他克莫司浓度超过15 ng/L治疗限度时出现。在本文中，我们介绍了一例肾移植受者出现恶心、头晕和疲劳症状的病例。
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