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Effect of mirtazapine on oxidative stress created in rat kidneys by ischemia-reperfusion.米氮平对缺血再灌注引起的大鼠肾脏氧化应激的影响。
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Biochemical and histopathological investigation of the protective effect of disulfiram in ischemia-induced ovary damage.二硫仑对缺血性卵巢损伤的保护作用的生化和组织病理学研究。
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Investigation of the effects of the chronic administration of some antihypertensive drugs on enzymatic and non-enzymatic oxidant/antioxidant parameters in rat ovarian tissue.研究慢性给予某些抗高血压药物对大鼠卵巢组织中酶和非酶氧化应激/抗氧化参数的影响。
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组织损伤与氧化/抗氧化平衡。

Tissue damage and oxidant/antioxidant balance.

作者信息

Kisaoglu Abdullah, Borekci Bunyamin, Yapca O Erkan, Bilen Habib, Suleyman Halis

机构信息

Department of General Surgery, Faculty of Medicine, Ataturk University, Erzurum, Turkey.

Department of Obstetrics and Gynecology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.

出版信息

Eurasian J Med. 2013 Feb;45(1):47-9. doi: 10.5152/eajm.2013.08.

DOI:10.5152/eajm.2013.08
PMID:25610248
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4261508/
Abstract

The oxidant/antioxidant balance in healthy tissues is maintained with a predominance of antioxidants. Various factors that can lead to tissue damage disrupt the oxidant/antioxidant balance in favor of oxidants. In this study, disruptions of the oxidant/antioxidant balance in favor of oxidants were found to be a consequence of the over-consumption of antioxidants. For this reason, antioxidants are considered to be of importance in the prevention and treatment of various types of tissue damage that are aggravated by stress.

摘要

健康组织中的氧化还原平衡以抗氧化剂占主导地位的方式得以维持。各种可能导致组织损伤的因素会破坏氧化还原平衡，使氧化剂占优势。在本研究中，发现氧化还原平衡向氧化剂方向的破坏是抗氧化剂过度消耗的结果。因此，抗氧化剂在预防和治疗因应激而加重的各种类型的组织损伤方面被认为具有重要意义。