Salikhbaeva U S, Kozlovskaia L V, Zaĭtseva L I, Kulagina N N, Kapinos E N
Ter Arkh. 1989;61(11):134-7.
A total of 46 patients with reactive arthritides and 20 patients with rheumatoid arthritis (RA) were examined, as compared with 20 normal persons, for the blood serum content of the products of catabolic breakdown of cell receptors--R proteins (according to inhibition of the hemagglutination reaction between human red blood cells and anti-R-serum) and for conventional parameters of phagocyte function of leukocytes. The content of R proteins in patients with reactive arthritis and RA was found to be increased, and the phagocytic activity was discovered to be lowered. The changes in the parameters indicated depended on the disease entity and the disease course. The possible pathophysiological importance of changes in the level of R proteins in arthritides is discussed.
对46例反应性关节炎患者和20例类风湿关节炎（RA）患者进行了检查，并与20名正常人进行比较，检测了细胞受体分解代谢产物——R蛋白的血清含量（根据人红细胞与抗R血清之间血凝反应的抑制情况）以及白细胞吞噬功能的常规参数。发现反应性关节炎和RA患者的R蛋白含量增加，吞噬活性降低。上述参数的变化取决于疾病类型和病程。文中讨论了关节炎中R蛋白水平变化可能的病理生理意义。
