U.S. Department of Health and Human Services, Office of the Assistant Secretary for Health, Division of Blood and Tissue Safety and Availability, Washington, DC.
Am J Transplant. 2015 Feb;15(2):547-54. doi: 10.1111/ajt.13006.
While the risk of infectious disease transmission through blood transfusion has been greatly reduced as a result of improved screening methods, transfusion-transmissible infections remain a concern for transplant recipients, especially those receiving multiple transfusions. Although transfusion and transplant recipients are at risk for similar infections, the current reporting requirements for infections transmitted by transfusions and organ transplantation vary greatly and remain distinctly separate with no communication between reporting systems. This article reviews 23 past reports of transfusion-transmitted infections in organ recipients acquired through transfusions. While cytomegalovirus was a major focus of such reports in the 1980s, more recent reports have focused on West Nile virus transmission. Additionally, this article highlights challenges in determining transfusion-transmitted infection risk in transplant recipients related to the current reporting systems.
虽然由于改进的筛查方法，通过输血传播传染病的风险已经大大降低，但输血传播感染仍然是移植受者关注的问题，特别是那些接受多次输血的受者。尽管输血和移植受者都面临着类似的感染风险，但目前输血和器官移植传播感染的报告要求差异很大，报告系统之间没有任何沟通，仍然是明显分开的。本文回顾了 23 份过去关于通过输血获得的器官受者输血传播感染的报告。虽然巨细胞病毒是 20 世纪 80 年代此类报告的主要关注点，但最近的报告重点是西尼罗河病毒的传播。此外，本文还强调了与当前报告系统相关的确定移植受者输血传播感染风险的挑战。
