Frati-Munari A C, de León C, Ariza-Andraca R, Bañales-Ham M B, López-Ledesma R, Lozoya X
Arch Invest Med (Mex). 1989 Jul-Sep;20(3):211-6.
To assess if a dehydrated extract of nopal stems retains the effect on glycemia of the entire nopal stems two experiments were performed. A. Six patients with type II diabetes mellitus in fasting condition received 30 capsules containing 10.1 +/- 0.3 g of the extract, and serum glucose levels were measured hourly from 0 to 180 minutes. B. Six healthy volunteers received 30 capsules with the extract followed by 74 g of dextrose orally. Serum glucose measurements were made in a similar fashion. In each experiment a control test with empty capsules was performed. Nopal extract did not reduce fasting glycemia in diabetic subjects. Nevertheless, the extract diminished the increase of serum glucose which followed a dextrose load. Peak serum glucose was 20.3 +/- 18.2 mg/dl (X +/- SD) lower in the test with nopal than in the control one (P less than 0.025). Dehydrated extract of nopal (Opuntia ficus-indica Mill) did not show acute hypoglycemic effect, although could attenuate postprandial hyperglycemia.
为评估仙人掌茎干脱水提取物是否保留了整个仙人掌茎干对血糖的影响，进行了两项实验。A. 六名处于空腹状态的II型糖尿病患者服用了30粒含有10.1±0.3克提取物的胶囊，并在0至180分钟内每小时测量一次血清葡萄糖水平。B. 六名健康志愿者服用30粒含有该提取物的胶囊，随后口服74克葡萄糖。血清葡萄糖测量以类似方式进行。在每个实验中，都进行了空胶囊对照试验。仙人掌提取物并未降低糖尿病受试者的空腹血糖。然而，该提取物减少了葡萄糖负荷后血清葡萄糖的升高。与对照试验相比，服用仙人掌提取物的试验中血清葡萄糖峰值低20.3±18.2毫克/分升（X±标准差）（P<0.025）。仙人掌（仙人掌属印度榕）脱水提取物未显示出急性降血糖作用，尽管其可减轻餐后高血糖。
